Shanghai Jiao Tong University

Shanghai United Imaging Intelligence Co., Ltd.

Sirnaomics, Inc.

Sirnaomics Medicine Technology (suzhou) Co, Ltd.

Qingfeng Li

Feng Shi

Yiqiang Zhan

Bokai Li

Quan Huo

Patrick Y Lu

Xiaolu Huang

Vera Simonenko

John Xu

Xiao Liang

Kerong Dai

Jia Zhou

Bangda Chai

Yaokai Gan

A composition of drug targets and the method of using thereof. The composition comprises a vector and a drug using FKBP10 and PCOLCE genes and/or the encoded proteins thereof as drug targets.

Composition of drug targets and method of using thereof

The current invention provides a method of activating fibroblast and myofibroblast apoptosis in a tissue of a mammal, comprising administering to the tissue a therapeutically effective amount of a composition comprising an siRNA molecule that binds to an mRNA that codes for TGFB1 protein in a mammalian cell, an siRNA molecule that binds to an mRNA that codes for COX-2 protein in a mammalian cell, and a pharmaceutically acceptable carrier comprising a pharmaceutically acceptable histidine-lysine polymer. The invention also provides additional methods for using this composition.

Pharmaceutical compositions and methods of use for activation of human fibroblast and myofibroblast apoptosis

A method for assessing a condition of an organ or tissue of a target object is provided. The method may include: obtaining a target image of the target object; segmenting a target region from the target image, the target region of the target image corresponding to a sub-region of the organ or tissue; determining a morphological characteristic value of the target region in the target image; obtaining a reference standard associated with a sample organ or tissue of a plurality of sample objects, the sample organ or tissue being of a same type as the organ or tissue of the target object; and assessing the condition of the organ or tissue of the target object by comparing the morphological characteristic value of the target region in the target image with the reference standard.

Systems and methods for image processing

Disclosed is a skin dilator, comprising an expander (), a pipe network provided on the skin-side surface wall () of the expander () composed of longitudinal tube () and horizontal tube () having a reticular structure and communicating with each other, and a guide tube () communicating with the pipe network. The skin dilator further comprises several burrs () distributed on the skin-side surface wall () of the expander (), and several small apertures () communicating the inner cavity of the tube with the outside are provided on both of the longitudinal tube () and horizontal tube(). The tissue expander can be infused biological agents by the filling port to the skin expanding site through the small apertures (), which may accelerate the expansion growth of skin, prevent skin complications, such as necrosis.

Skin dilator

Growing community of inventors

Shanghai, China

Qingfeng Li