Jiangsu Transimage Technology Co., Ltd.

Hand Held Products, Inc.

Legend Biotech Ireland Limited

Other

Inspur Suzhou Intelligent Technology Co., Ltd

Suzhou Lixin Pharmaceutical Co., Ltd.

Qing Zhang

Jie Ren

Shu Wu

Haiming Qu

Yafeng Zhang

Tailan Zhan

Chen Feng

Jian Liu

Xuenong Xu

Jun Lu

Feng Li

Wang Zhang

Feng Chen

Yun Zhang

Jia Xue

Jian Su

Fei Sun

Zhe Wang

Xiaojie Tu

Deli Zeng

Wenjie Zhou

Yunlei Liu

Lingling Xie

An Tang

Liang Shu

Chenyu Shu

Bing Zhao

Zhijian Bao

Disclosed is a method for training an abnormal-detection model based on an improved denoising autoencoder, including: acquiring an original image; generating a rectangular frame according to a preset range of a resolution ratio, by the improved denoising autoencoder, and occluding the original image by the rectangular frame, wherein the resolution ratio is a ratio of a resolution of an occlusion area formed by the rectangular frame to a resolution of the original image; filling random noise in the rectangular frame to obtain a noised image, by the improved denoising autoencoder; and performing constraint learning on the original image and the noised image, by the abnormal-detection model, to implement training of the abnormal-detection model. Because a learning task is more complex, it is helpful to alleviate identity mapping, and detection performance of the model is improved. The present application further provides an apparatus, a device, and a readable storage medium thereof.

Noise reduction auto-encoder-based anomaly detection model training method

The present application provides single-domain antibodies targeting CD33 and constructs thereof, including chimeric receptors, immune effector cell engagers and immunoconjugates. Further provided are engineered immune cells (such as T cells) comprising an anti-CD33 chimeric receptor and optionally a second chimeric receptor targeting a second antigen or epitope. Pharmaceutical compositions, kits and methods of treating cancer are also provided.

Single-domain antibodies against CD33 and constructs thereof

Provided are single-domain antibodies targeting CLL1 and constructs thereof, including chimeric receptors, immune effector cell engagers and immunoconjugates. Further provided are engineered immune effector cells (such as T cells) comprising an anti-CLL1 chimeric receptor and optionally a second chimeric receptor targeting a second antigen or epitope. Pharmaceutical compositions, kits and methods of treating cancer are also provided.

Single-domain antibodies against CLL1 and constructs thereof

Examples embodiments of a method and system for synchronizing active illumination pulses in a multi-sensor imager is provided. Example embodiments of the method disclosed herein include the provision of an illumination pulse for each of N sensors, each of N illumination pulses are set to have the same pulse period and active pulse width. Moreover, example embodiments include setting the active width pulse for each of the N illumination pulses to have maximum exposure time for each of N image sensors, and in further examples, ensuring that the time to capture a frame plus the time interval between subsequent image captures is the same for each sensor. In yet further examples, an offset period between subsequent frame synchronous signals is determined. In yet further example embodiments, an interval between frame captures is adjusted and a negative edge of the frame synchronous signal and an illumination pulse is aligned.

Method and system for synchronizing illumination timing in a multi-sensor imager

A key structure of a keyboard includes a keycap, a scissor connecting mechanism, a conductive circuit board and a bottom plate from top to bottom, wherein a projection is arranged between the scissor connecting mechanism and the conductive circuit board; when an optional position of the periphery of the keycap is pressed, the scissor connecting mechanism is in contact with the projection before the conductive circuit board or the bottom plate below the scissor connecting mechanism; and if the optional position of the periphery of the keycap continues being pressed, the scissor connecting mechanism positioned on one side of the pressed point is bent and deformed by using the projection as a fulcrum and is in contact with the conductive circuit board.

Key structure of keyboard

A scissor structure for a key of a keyboard includes an inner scissor and an outer scissor, wherein the inner scissor is fixedly connected with the outer scissor through an elastic connecting pin; when the key is pressed, the inner scissor and the outer scissor are pressed therewith, and drive the elastic deformation of the connecting pin; when the key is loosened, the inner scissor and the outer scissor are restored to an initial state under the elastic restoring force of the connecting pin, so as to transmit the key.

Scissor structure for key of keyboard

Disclosed in the present invention is a method for preparing nilotinib intermediate 3-(4-methyl-1H-imidazol-1-yl)-5trifluoromethyl phenylamine (I). The method comprises the following steps: taking trifluorotoluene as an initial material, and preparing the nilotinib intermediate (I) by nitration, bromization, condensation and reduction successively Compared with the prior art, the preparation method has the following advantages: a relatively high yield, the raw materials are easily obtained, a concise process and few side reactions, and is adapted to industrial production, so the development of an economic technology of the bulk drug is promoted.

Method for preparing nilotinib intermediate

A keyboard structure includes an elastomer, a flexible conductor and a conductive circuit board from top to bottom. The conductive circuit board is respectively provided with a circuit anode and a circuit cathode, the flexible conductor includes a flexible body and a conductive layer arranged on the flexible body. When pressing the elastomer, the circuit is switched on if the conductive layer on the flexible conductor is in contact with the circuit anode and the circuit cathode on the conductive circuit board. When loosening the elastomer, the circuit is switched off if the conductive layer on the flexible conductor is separated from the circuit anode and the circuit cathode on the conductive circuit board.

Keyboard structure

A balancing structure for a long key of a keyboard includes a balancing rod and a pair of clamping hooks arranged on a bottom plate of the keyboard. The balancing rod includes a cross rod matched with a keycap of the key and two sliding rods extending from two end parts of the cross rod and matched with the pair of clamping hooks respectively. During the keycap pressing or spring-back process, each of the two sliding rods slides on a clamping port edge on at least one side of the corresponding clamping hook along with the rotation of the cross rod, and the moving trajectory of the contact point of each sliding rod and the corresponding port edge is an arc in the sliding process.

Balancing structure for long key of keyboard

Systems and methods for cancelling noise caused by the flicker of ambient lights are provided. Such noise cancelling systems and methods may be incorporated in a laser-based barcode scanning device. In one example, a barcode scanning device includes a light source, a first sensor, a second sensor, and a noise cancelling circuit. The light source is configured to emit a beam of light. The first sensor is configured to detect a first optical signal indicative of light reflecting off of a barcode. The reflected light may originate from the light source and from at least one ambient light source in the vicinity of the barcode scanning device. The second sensor is configured to detect a second optical signal indicative of light originating from the at least one ambient light source. The noise cancelling circuit is configured to obtain a noise-cancelled scanning signal from the first and second optical signals.

Cancelling noise caused by the flicker of ambient lights

Growing community of inventors

Jiangsu, China

Qing Zhang