Monsanto Technology LLC

Monsanto Company

Harvard College

Qing Huai

Victor M Guzov

David R Liu

Thomas M Malvar

Larry A Gilbertson

Artem G Evdokimov

Sergey Ivashuta

Ahmed Hussein Badran

Prashanth Vishwanath

Brian Edward Weiner

Jeffrey A Haas

Timothy K Ball

Tom Malvar

Jeff Nageotte

Melissa M Kemp

Melissa Kemp

Parthasarathy Ramaseshadri

Byron V Olsen

Yifei Kong

Pesticidal proteins are provided that combine two or more modes of action into a single molecule. These pesticidal proteins therefor exhibit greater efficacy and/or durability of resistance, for the purposes of pest control, and can be utilized for pest control by provision in the diet of a pest organism, or by topical application to crop plants and/or pests. Methods and compositions for producing and using such proteins are also provided.

Multi functional toxins

The disclosure provides amino acid sequence variants of(Bt) toxins and methods of producing the same. Some aspects of this disclosure provide methods for generating Bt toxin variants by continuous directed evolution. Some aspects of this disclosure provide compositions and methods for pest control using the disclosed variant Bt toxins.

Evolution oftoxins

Growing community of inventors

Winchester, MA, United States of America

Qing Huai