Rutgers, the State University of New Jersey

Qing Cui

Walter Welkowitz

Yun Qi

Apparatus for noninvasively monitoring cardiovascular system parameters of a living subject comprises means for sensing waveforms externally of the body of the subject above the carotid and femoral arteries, means for non-invasively calibrating and digitizing the pulse waveforms, and a digital signal processor having means for converting the digitized, calibrated pulse information by Fast Fourier Transform to first and second sets of harmonically related blood pressure components in the frequency domain, means for comparing corresponding ones of the components in the first and second harmonically related sets to determine amplitude and phase transfer function components of the portion of the cardiovascular system between the carotid and femoral arteries, means for simulating the portion of the system by a hybrid electrical circuit model having at least three variable parameters, means for determining corresponding amplitude and phase transfer function components of the hybrid model and for adjusting the variable parameters so as to substantially match the transfer functions of the model and the portion of the cardiovascular system, and means for determining cardiac output utilizing the adjusted parameters of the hybrid model and the calibrated pulse information.

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Highland Park, NJ, United States of America

Qing Cui