Aat Bioquest, Inc.

Affymetrix, Inc.

Qin Zhao

Zhenjun Diwu

Haitao Guo

Ruogu Peng

Jixiang Liu

Jinfang Liao

Travis Jennings

Castle Funatake

Feng Quan Liu

Fluorescent water soluble conjugated polymers including polycyclic aromatic comonomers are provided. The conjugated polymers can be linked to an acceptor fluorescent dye. The conjugated polymers find use in conjugates with biological substrates having applications in a variety of applications including methods of analyte detection.

Condensed polycyclic conjugated polymers and their use for biological detection

The invention provides for polyfluoreno[4,5-cde]oxepine conjugates and their use in methods of analyte detection.

Polyfluoreno[4,5-cde]oxepine conjugates and their use in methods of analyte detection

Polyfluoreno[4,5-cde]oxepine polymers and conjugates thereof

The present disclosure provides fluorogenic compounds useful for preparing fluorescent calcium ion indicators, the fluorescent indicators themselves, and the use of the fluorescent indicators in methods of detection, discrimination and quantification of metal ions. The subject fluorogenic compounds and fluorescent ion indicators can include a chelating group based on a 2-aminophenoxyethylene glycol 2-aminoethyl ether, N,N,N',N&#x2032;-tetraacetic acid (PEGTA) moiety or precursor thereof where the phenyl group of the PEGTA is substituted with or fused with a fluorophore moiety of interest. The subject methods find use in the detection of intracellular calcium ions. Also provided are kits for use in practicing the subject methods.

Fluorogenic calcium ion indicators and methods of using the same

Fluorescent dyes useful for preparing fluorescent metal ion indicators, the fluorescent indicators themselves, and the use of the fluorescent indicators for the detection, discrimination and quantification of metal cations are provided.

Carbofluorescein lactone ion indicators and their applications

Growing community of inventors

Sunnyvale, CA, United States of America

Qin Zhao