Shenzhen Chipscreen Biosciences Co., Ltd.

Shenzhen Chipscreen Biosciences, Ltd.

Qianjiao Yang

Zhibin Li

Xianping Lu

Song Shan

Lijun Xin

Desi Pan

Yonglian Song

Xianghui Wang

Yu Zhang

Zhiqiang Ning

Chao Fu

Jindi Yu

Xiaoliang Wang

Jiangfei Zhu

Xiangheng Liu

Qi Wei

Huiyun Huang

A biphenyl compound represented by formula (I), a preparation method therefor and an application thereof. The present invention also relates to a pharmaceutical composition that comprises the compound as an active ingredient. The compound is a novel small molecule immunomodulator having excellent oral absorption features and can be used for treating and/or preventing various immunity-related diseases.

Biphenyl compound as immunomodulator, preparation method therefor and application thereof

The present invention relates to a urea compound and a preparation method and an application thereof. The structure of the present compound is represented by formula (I), the definition of each variable in the formula being as described in the description. The compound can block interaction between the PD-1/PD-L1 signalling pathways. The compound of the present invention can be used for treating or preventing diseases related to the signalling pathways, such as cancer, autoimmune disease, chronic infectious disease, and other diseases. 

Urea compound and preparation method and application thereof

An application of a compound having general formula (I) as JAK3 and/or JAK1 kinase and a preparation method for the compound.

Preparation method for aromatic heterocyclic compound used as selective JAK3 and/or JAK1 kinase inhibitor and application of aromatic heterocyclic compound

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Guangdong, China

Qianjiao Yang