Accure Health, Inc.

Qiang Liu

Liyun Sang

Guang Chen

Yi Liu

Brian Wee

Embodiments of automated assay processing systems and methods are disclosed. In an example, an assay automation system includes an assay processing tube, a magnet, and a controller. The assay processing tube has a right arm and a left arm, the right arm having an opening for receiving reagent transferred from a reagent tube being held in one of the tube-holding arms of the reagent tube holder, the assay processing tube being driven to rotate. The magnet is driven to move vertically. The controller is configured to control coordinated movements of the assay processing tube and the magnet to perform an assay processing sequence.

Automated assay processing methods and systems

Embodiments of systems and methods for automated sample handling are disclosed. In an example, a system for automated sample handling includes reaction wells, a magnet, a magnetic manipulator, and a punch. The reaction wells are configured to each hold a reagent and collectively move horizontally. A first reaction well holds magnetic beads, and a second reaction well is partitioned by a seal. The magnet is configured to move vertically and capture the magnetic beads on a bottom surface of the first reaction well when moving to an upper position beneath the first reaction well. The magnetic manipulator is configured to manipulate the magnetic beads and includes a magnetic rod configured to move vertically to be above or in the first reaction well and a sheath below the magnetic rod and configured to move vertically and receive the magnetic rod. The punch is configured to move vertically and break the seal of the second reaction well when moving to a lower position in the second reaction well.

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Cambridge, MA, United States of America

Qiang Liu