International Business Machines Corporation

Shanghai East Hospital

Qian Zhao

Yu Wang

Ning Duan

Peng Ji

Jian Dong Ding

Jun Zhu

Chao Zhang

Jun Chi Yan

Jian Ding

Xin Zhang

Zhi Hu Wang

Peng Gao

Min Gong

Jianbin Tang

Junchi Yan

Feng Juan Wang

Chao E Zhang

Yi Qi

Ya Ming Zhang

Zhongmin Liu

Zuoren Yu

Ju Yuan

A microRNA (miRNA) inhibitor, being able to form a stable DNA-RNA double-stranded structure with a miRNA. The double-stranded structure comprises: (i) a miRNA unit sequence, and (ii) an RNA zipper unit sequence. The 5'-end of the RNA zipper unit sequence is connected to the 5&#x2032;-end of the miRNA unit sequence. The 3&#x2032;-end of the RNA zipper unit sequence is connected to the 3&#x2032;-end of the miRNA unit sequence. The RNA zipper can connect the head of the miRNA molecule to the tail of the miRNA molecule to form a stable long-chain structure. The RNA zipper unit sequence contains 1-3 nucleotides not connected to the miRNA unit sequence. The DNA-RNA double-stranded structure can be used to inhibit biological activities of a miRNA unit, does not have biological toxicity, and has the advantages of high affinity, high specificity and high stability.

MicroRNA inhibitor

The present disclosure relates to a method and system for generating a road network. An embodiment of the present invention provides a method comprising: identifying a target area to be refined in a road network skeleton; and refining the target area using at least one trajectory associated with the target area to generate the road network. Another embodiment of the present invention provides a corresponding system.

Generating a road network from location data

A method and system for handing off a terminal among a plurality of wireless access points (APs) connected to a central management AP. The method comprising: receiving network condition information of a terminal communicatively connected to a first wireless AP among the plurality of wireless APs. Determining a second wireless AP the plurality of wireless APs to which the terminal is to be handed off based on the network condition information of the terminal. The second wireless AP is virtually connected to the terminal. Submitting a handoff request to the second wireless AP. Notifying the terminal to hand off to the second wireless AP in response to receiving a handoff response from the second wireless AP.

Handing off a terminal among wireless access points

In an approach to determining an air quality based on image, a computer performs a method, the method comprising: determining an image to be measured; determining an air quality model of at least one key area, the at least one key area including a key area associated with the image to be measured; acquiring a reference clear image corresponding to the image to be measured; and determining an air quality index to be measured based on an air quality related feature extracted from the image to be measured, the corresponding reference clear image, and the determined air quality model of the key area associated with the image to be measured.

Method and apparatus of determining air quality

The present disclosure discloses a method and an apparatus for building a missing part of a movement path of an object. One or more frequent points is determined, wherein each of the one or more frequent points is a point on a historical movement path having a number of occurrences greater than a first threshold. A credibility of one or more path segments in determined. A first path segment of the one or more path segments is selected, wherein the credibility of the first path segment is greater than a second threshold. A missing part of a movement path of an object is built using the first path segment.

Building missing movement path of an object

A method and apparatus for vehicle position indexing. The method includes: obtaining position information of a vehicle in real time, and monitoring a current road segment where the vehicle is located based on the position information and road segment information divided by road network information; in response to having monitored that the vehicle enters into the current road segment, building a road segment index record that includes identification information of the vehicle, identification information of the current road segment, and a time when the vehicle enters into the current road segment; and in response to having monitored that the vehicle leaves the current road segment, adding the time when the vehicle leaves the current road segment, into the road segment index record.

Vehicle position indexing

A method for recommending a candidate path includes, in response to receiving a query from a user, looking up a plurality of paths that conform to the query; with respect to a current path among the plurality of paths, obtaining behavior data of the user and behavior data of at least one other user associated with the current path; determining a recommendation indicator associated with the current path, based on the behavior data of the user and the behavior data of the at least one other user; and recommending the candidate path to the user based on at least a recommendation indicator associated with at least one of the plurality of paths.

Candidate path recommendation

The present invention discloses a method and apparatus of determining air quality. The method comprising: determining at least one key area; acquiring a reference clear image, a training image under poor air quality and corresponding actual air quality index in at least one location of the key area; and training an air quality model of the key area based on feature extracted from the reference clear image and the training image and based on the actual air quality index. With the method and apparatus of the invention, air quality can be determined based on image.

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Shanghai, China

Qian Zhao