Gilead Sciences, Inc.

Gilead Pharmasset LLC

Qi Liu

Winston C Tse

John O Link

Scott D Schroeder

Jennifer R Zhang

Randall Halcomb

William John Watkins

Eda Y Canales

Scott E Lazerwith

Choung U Kim

Aesop Cho

Michael Graupe

Michael L Mitchell

Darryl Kato

Carina E Cannizzaro

Steven S Bondy

James G Taylor

Richard L Mackman

Manoj C Desai

Jeromy J Cottell

Elizabeth M Bacon

Lianhong Xu

Hongtao Liu

Hongyan Guo

Jianyu Sun

Randall W Vivian

Hyung-Jung Pyun

Gediminas J Brizgys

Edward Doerffler

Chandrasekar Venkataramani

Zheng-Yu Yang

Thorsten A Kirschberg

Jay P Parrish

Evan S Krygowski

Lee Shun Chong

Michael O'Neil Hanrahan Clarke

Roland D Saito

Barton W Phillips

Haolun Jin

Samuel E Metobo

Philip Anthony Morganelli

Ryan McFadden

Yunfeng Eric Hu

James D Trenkle

Joseph H Saugier

Chien-Hung Chou

Chien-hung Chou

Willard Lew

Martin Gerald Teresk

Shinji Fujimori

Jared Wayne Evans

Grace Huynh

Randall L Halcomb

John R Somoza

Michael R Mish

Terry Kellar

Yafan Lu

Michael O' Neil Hanrahan Clarke

Michael Mertzman

Hong Ye

Hyung-Jun Pyun

Ryan Mcfadden

Neil Squires

Xiaoning Sheng

James Taylor

Richard Mackman

Hongtae Liu

Thorstens A Kirschberg

Chuong U Kim

Grace M Huynh

Michael O'neil Hanrahan Clarke

Clarke; Michael O'Neil Hanrahan Hanrahan

Saugier; Joseph H H

Schroeder; Scott D D

Michael O'neil Clarke

The invention provides compounds of formula (I): or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus. 

Compounds for the treatment of HIV

The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

Antiviral compounds

Compounds of formula (I) or salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus. 

Therapeutic compounds

Compounds of formula I: or salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus.

Compounds of formula I: or pharmaceutically acceptable salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus.

The present disclosure provides processes for the preparation of a compound of Formula I: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates to compounds of formula.

Synthesis of an antiviral compound

The present disclosure provides a processes for the preparation of a compound of Formula I: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates to compounds of Formula I.

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Union City, CA, United States of America

Qi Liu