Gilead Sciences, Inc.

Gilead Pharmasset LLC

Qi Liu

Winston C Tse

John O Link

Scott D Schroeder

Jennifer R Zhang

Randall Halcomb

William John Watkins

Eda Y Canales

Scott E Lazerwith

Choung U Kim

Aesop Cho

Yunfeng Eric Hu

Michael Graupe

Michael L Mitchell

Darryl Kato

Carina E Cannizzaro

Steven S Bondy

James G Taylor

Richard L Mackman

Manoj C Desai

Jeromy J Cottell

Elizabeth M Bacon

Lianhong Xu

Jay P Parrish

Hongtao Liu

Hongyan Guo

Jianyu Sun

Randall W Vivian

Evan S Krygowski

Hyung-Jung Pyun

Chandrasekar Venkataramani

Zheng-Yu Yang

Thorsten A Kirschberg

Lee Shun Chong

Michael O'Neil Hanrahan Clarke

Gediminas J Brizgys

Edward Doerffler

Roland D Saito

Willard Lew

Barton W Phillips

Haolun Jin

Samuel E Metobo

Philip Anthony Morganelli

Michael R Mish

Ryan McFadden

James D Trenkle

Joseph H Saugier

Chien-Hung Chou

Chien-hung Chou

Martin Gerald Teresk

Shinji Fujimori

Jared Wayne Evans

Grace Huynh

John R Somoza

Yafan Lu

Michael O' Neil Hanrahan Clarke

Michael Mertzman

Hong Ye

Hyung-Jun Pyun

Hongtae Liu

Michael O'neil Hanrahan Clarke

Thorstens A Kirschberg

Neil Squires

Chuong U Kim

Xiaoning Sheng

Terry Kellar

James Taylor

Grace M Huynh

Clarke; Michael O'Neil Hanrahan Hanrahan

Saugier; Joseph H H

Schroeder; Scott D D

Randall L Halcomb

Richard Mackman

Ryan Mcfadden

Michael O'neil Clarke

The invention provides compounds of formula (I): or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus. 

Compounds for the treatment of HIV

The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

Antiviral compounds

Compounds of formula (I) or salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus. 

Therapeutic compounds

Compounds of formula I: or salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus.

Compounds of formula I: or pharmaceutically acceptable salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus.

The present disclosure provides processes for the preparation of a compound of Formula I: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates to compounds of formula.

Synthesis of an antiviral compound

The present disclosure provides a processes for the preparation of a compound of Formula I: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates to compounds of Formula I.

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Union City, CA, United States of America

Qi Liu