Beijing Forelandpharma Co. Ltd.

Foreland Pharma Co., Ltd.

Legao Leija (beijing) Information Technology Co., Ltd.

Qi Ji

Lei Wang

Xingmin Zhang

Zhenjian Du

Congmin Gao

Longlong Gong

Bo Chen

Ensi Wang

Yuan Haoyang

Wu Xian

Meijing Du

The present invention belongs to the field of medicine, and specifically discloses an amino alcohol derivative represented by Formula I, a pharmaceutically acceptable salt, solvate, polymorph or prodrug thereof. In addition, the present invention also discloses a pharmaceutical composition comprising the above substances, and a use of the substance in the preparation of a medicament for the prevention and treatment of an immune inflammatory disease, or a disease or condition associated with immunological competence such as multiple sclerosis, ALS, CIDP, systemic lupus erythematosus, rheumatoid arthritis, ulcerative colitis, psoriasis, polymyositis, etc.

Amino alcohol derivative, pharmaceutical composition and application thereof

The present invention relates to the crystal form of imidazolone type compounds, and a preparation method, pharmaceutical composition and use thereof, and falls within the field of pharmaceutical compound crystals. The crystal form provided by the present invention has a good stability, comprising good stability under the three extreme conditions of high temperature, high humidity and strong illumination, and can also maintain a good stability during the tablet compressing process. The crystal form provided by the present invention has good absorption and metabolism properties in vivo, comprising the drug concentration of blood, the drug concentration-time curve AUC, the half-life period, etc. In addition, the dissolving rate of the crystal form of the present invention is improved, wherein same is beneficial for the applications thereof in preparations.

Crystal form of imidazolone type compounds, and preparation method, pharmaceutical composition and use thereof

This application relates to imidazolone compounds, pharmaceutically acceptable salts, solvents, polymorphs or prodrugs thereof, and further relates to pharmaceutical combinations comprising the foregoing substances and uses for preventing and treating protein kinase related diseases such as cancer, metabolic diseases, and cardiovascular diseases.

Imidazolone derivatives, pharmaceutical compositions and uses thereof

A network system for positioning services based on wireless communication system, including base stations, a dedicated access apparatus, cables, and a server. The base stations, the dedicated access apparatus and the cables constituting a private network. The server constituting a public network. The base stations are configured to send and receive signals in a broadcasting manner, and transmit the signals to the server through the cables and the dedicated access apparatus. The dedicated access apparatus is configured to transfer transmission data between the private network and the public network, forward data from the base stations to the server, and forward data from the server to a corresponding base station. The cables are configured to transmit data between the base stations and between the base stations and the dedicated access apparatus. The server is configured to perform data processing according to the received data collected by at least one base station.

Network system for positioning services based on wireless communication technologies

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Beijing, China

Qi Ji