Jubilant Epicore LLC

Purushottam Dewang

Sriram K Rajagopal

Sridharan Rajagopal

Chandrika Mulakala

Dhanalakshmi Sivanandhan

Subramanyam Janardhan Tantry

Pravin Iyer

Chandru Gajendran

Kannan Murugan

Sreekala Nair

Mahanandeesha S Hallur

Mohd Zainuddin

Durga Prasanna Kumar C H

Durga Prasanna Kumar CH

The present disclosure describes novel compounds of the general Formula (I), their analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites, and prodrugs thereof. These compounds can inhibit both LSD and HDAC and are useful as therapeutic or ameliorating agent for diseases that are involved in cellular growth such as malignant tumors, schizophrenia, Alzheimer's disease, parkinson's disease and the like.

Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors

The present disclosure describes novel compounds of the general Formula (I), their analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites, and prodrugs thereof. These compounds can inhibit both LSD and HDAC and are useful as therpeautic or ameliorating agent for diseases that are involved in cellular growth such as malignant tumors, schizophrenia, Alzheimer's disease, parkinson's disease and the like. 

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Bengaluru, India

Purushottam Dewang