Ranbaxy Laboratories, Inc.

Banbaxy Laboratories Limited

Purna Chandra Ray

Naresh Kumar

Mohammad Salman

Jayachandra Suresh Babu

Yatendra Kumar

Jag Mohan Khanna

Chandra Has Khanduri

Brij Khera

J Suresh Babu

Sujay Biswas

The present invention relates to a cost effective and industrially advantageous process for the preparation of repaglinide.

Process for the preparation of repaglinide

The present invention relates to an industrial useful process for the synthesis of antiviral compound, ganciclovir which comprises dissolving a mixture containing N-7 and N-9 isomers of structural formulae, II and III, respectively:in a solvent or a mixture of solvents; separating the N-7 and N-9 isomers; and hydrolizing the N-9 isomer to obtain ganciclovir.

Process for the synthesis of ganciclovir

The present invention relates to a new and industrially advantageous process for the preparation of 3-ethoxy-4-ethoxy-carbonyl-phenyl acetic acid. This compound is a key intermediate for the synthesis of Repaglinide, an oral hypoglycemic agent.

Synthesis of 3-ethoxy-4-ethoxycarbonyl phenyl acetic acid, a key acid synthon of repaglinide

A process for the manufacture of pharmaceutical grade ranitidine base(N-�2-���5-(Dimethylamino)methyl!-2-furanyl!methyl!thio!ethyl-N'-methy l-2-nitro-1, 1-ethenediamine), is described. In-vitro and in-vivo pharmacological studies and acute toxicity studies indicate that it is as active and as safe as Form 2 ranitidine hydrochloride.

Process for the manufacture of pharmaceutical grade ranitidine base

Growing community of inventors

Delhi, India

Purna Chandra Ray