Japan Advanced Institute of Science and Technology

Punnida Nonsuwan

Kazuaki Matsumura

A hydrogel of which the degradation is accurately controlled can be provided by a photodegradable hydrogel production method, the method comprising the steps of: reacting α-glucan having a weight average molecular weight of 2000 to 200,000 with a compound represented by formula I to introduce a group represented by formula II into the α-glucan; oxidizing the α-glucan having, introduced therein, the group represented by formula II with periodic acid or a periodate salt to introduce an aldehyde group into the α-glucan; and adding aminated carrageenan gel beads having polydopamine particles embedded therein to a gelling agent which has been prepared by introducing a group represented by formula II and an aldehyde group into α-glucan, and then causing the crosslinking reaction of the resultant product with a polythiol-type reducing agent to form the hydrogel.

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Ishikawa, Japan

Punnida Nonsuwan