Stmicroelectronics S.r.l.

Altergon Sa

Principia Dardano

Maria Fortuna Bevilacqua

Luigi Nicolais

Andrea Di Matteo

Vincenza Di Palma

Luca De Stefano

Ilaria Rea

The object of the present invention is a device () for the transdermal delivery of active molecules. The device () comprises a support element () and a plurality of micro-needles () that protrude from a first surface of the support element (), the support element () and the micro-needles () being both permeable to the active molecules. The device () further comprises a porous membrane () configured to be loaded with said active molecules, which lies on a second surface of the support element (). Characteristically, the porous membrane () is configured to behave, from an optical viewpoint, as a Bragg mirror. Further objects of the present invention are the following uses of the device (): for monitoring the release and/or the decay of the active molecules, for the optical control of the release of the active molecules and for the thermal control of the release of the active molecules. Lastly, an object of the present invention is the method for producing the device () for transdermal delivery of active molecules.

Device for transdermal delivery of active molecules, uses of the device and methods for producing the device and its components

A microneedle array device includes a substrate and an array of microneedles on the substrate. Each microneedle includes a redox enzyme and redox mediator and an electrically conductive layer on the substrate. The electrically conductive layer may extend partway up each microneedle exposing the tip thereof.

Microneedle array device and method of making

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Ercolano, Italy

Principia Dardano