Roussel Uclaf

Primo Rizzi

Jean Jolly

Rene Heymes

Jean A Grandadam

Bernard Matra

Jean Taillardat

A novel process for the preparation of syn isomers of cephalosporanic acid derivatives of the formula ##STR1## comprising reacting first in a solvent and optionally in the presence of a base, a compound of the formula ##STR2## with a compound of the formula

Process for the preparation of derivative of

The monohydrate of 1.alpha.,25-dihydroxy-cholecalciferol having a remarkable vitamin activity and a process for its preparation.

1.alpha.,25.alpha.-Dihydroxy-cholecalciferol and methods for the

The novel product, dextrorotary 7-bromo-6-chloro-3-[3-(3-hydroxy-2-piperidyl)-acetonyl]-4(3H)-quinazolinon e and its non-toxic, pharmaceutically acceptable acid addition salts having anticoccidiosis activity and its preparation and use.

Novel quinazolinone

Novel 4,5-seco-estrane-3,5,17-trione derivatives of the formula ##STR1## wherein R.sub.1 is alkyl of 1 to 3 carbon atoms, R.sub.2 is selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms and K and K' are individually blocked ketones in the form of ketals which are intermediates for the preparation of therapeutically active steroids and their preparation and novel intermediates.

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Villemomble, France

Primo Rizzi