University of California

Preston B Landon

Ratneshwar Lal

Alexander Mo

Joon Bok Lee

Gennadi V Glinskii

Michael Taeyoung Hwang

Srinivasan Ramachandran

Brian Meckes

Methods, systems, and devices are disclosed for fabricating and implementing nanoscale and microscale structured carriers to provide guided, targeted, and on-demand delivery of molecules and biochemical substances for a variety of applications including diagnosis and/or treatment (theranostics) of diseases in humans and animals. In some aspects, a nanostructure carrier can be synthesized in the form of a nanobowl, which may include an actuatable capping particle that can be opened (and in some implementations, closed) on demand. In some aspects, a nanostructure carrier can be synthesized in the form of a hollow porous nanoparticle with a functionalized interior and/or exterior to attach payload substances and substances for magnetically guided delivery and controlled release of substance payloads.

Nanostructured carriers for guided and targeted on-demand substance delivery

Methods, systems, and nano-sensor devices are disclosed for detecting or discriminating nucleic acids with a single nucleotide resolution based on nucleic acid strand displacement. The detection can be made by time-lapse fluorescence measurements or by electro-based graphene FET, which can be combined with wireless communication to provide real-time transmission of the detected signals.

Nano-sensors for nucleic acid detection and discrimination

Growing community of inventors

San Diego, CA, United States of America

Preston B Landon