Incyte Pharmaceuticals, Inc.

Incyte Genomics, Inc.

Incyte Corporation

Xdx, Inc.

Other

Inctye Corporation

Incyte Pharamceuticals, Inc.

Preeti G Lal

Neil C Corley

Olga Bandman

Jennifer L Hillman

Purvi Shah

Karl J Guegler

Henry Yue

Y Tom Tang

Mariah R Baughn

Janice K Au-Young

Chandra Patterson

Matthew R Kaser

Chandra S Arvizu

Surya K Goli

April J A Hafalia

Dyung Aina M Lu

Monique G Yao

Ameena R Gandhi

Yan Lu

Neil Burford

Li Ding

Junming Yang

Roopa M Reddy

Ingrid E Akerblom

Gina A Gorgone

Yalda Azimzai

Anita Swarnakar

Craig H Ison

Bridget A Warren

Yuming Xu

Brendan M Duggan

Narinder K Chawla

Bao M Tran

Sally Lee

Kimberly J Gietzen

Madhusudan M Sanjanwala

Gina A Gorgone Simone

Michael Thorton

Cynthia D Honchell

Danniel B Nguyen

Vicki S Elliott

Catherine M Tribouley

Jennifer L Jackson

Narinder K Walia

Lynn E Murry

Kavitha Thangaveln

Stephanie Kareht

Farrah A Khan

Phillip R Hawkins

Hong Zhang

Rajagopal Gururajan

Joanne R Petithory

Preete Mathur

Jayalaxmi Ramkumar

Roopa Reddy

Kavitha Thangavelu

Tom Y Tang

Jennifer L Policky

Stephanie K Sapperstein

Debopriya Das

Vicki S Kaulback

Jeffrey J Seilhamer

Kirk E Fry

Ernestine A Lee

Jay Wohlgemuth

Angelo M Delegeane

Scott R Panzer

Russell L Dedrick

Gary B Zweiger

Michael B Thornton

Ian J Forsythe

Mary Jane Cunningham

Samuel T Labrie

Liam Kearney

Deborah A Kallick

Mark L Borowsky

Roberto Hernandez

Sajeev Batra

Gavin E Williams

Jingtao Sun

Darren Tayama

Dirk Walther

Vicki S Elliott Kaulback

Jennifer A Griffin

Stephen Todd

The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

Secreted proteins

The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.

Methods for detecting expression levels of human signal peptide-containing proteins (HSPP)

Methods for treating colon cancer and inflammation associated with overexpression of human signal peptide-containing proteins

Antibodies which bind to signal peptide-containing molecules

Antibody to secreted polypeptide

Compositions comprising signal peptide-containing proteins

The invention provides human transmembrane proteins (HTMPN) and polynucleotides which identify and encode HTMPN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HTMPN.

Human transmembrane proteins

Polynucleotides encoding signal peptide-containing molecules

The invention presents a method of diagnosing or monitoring the status of systemic lupus erythematosus (SLE) in a subject or patient comprising detecting the expression of all genes of a diagnostic set in the subject or patient wherein the diagnostic set comprises two or more genes having expression correlated with the classification or status of SLE; and diagnosing or monitoring the status of SLE in the subject or patient by applying at least one statistical method to the expression of the genes of the diagnostic set.

Methods for diagnosing and monitoring the status of systemic lupus erythematosus

The invention provides three human vesicle trafficking proteins (VTP) and polynucleotides which identify and encode VTP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of VTP.

Vesicle trafficking proteins

Described herein is a system for monitoring gene expression for diagnosing and monitoring inflammation disorders, and for monitoring gene expression in inflammation disorders in response to a particular drug treatment regimen. This system for detecting nucleic acid expression in a body fluid uses an isolated polynucleotide to detect expression of a nucleic acid comprising a nucleotide sequence selected from the group consisting of SEQ ID NO: 5; SEQ ID NO:11; SEQ ID NO:17; and SEQ ID NO: 23. These nucleic acids are differentially expressed in body fluid in an individual with a disease criterion for a disease as listed in Table 1 as compared to an individual without the disease criterion.

Genes useful for diagnosing and monitoring inflammation related disorders

The invention provides human molecules associated with cell proliferation (MACP) and polynucleotides which identify and encode MACP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of MACP.

Polynucleotides encoding molecules associated with cell proliferation

Growing community of inventors

Santa Clara, CA, United States of America

Preeti G Lal