Novo Nordisk A/s

Preben Broskov Nielsen

Henrik Sune Andersen

Lars Peter Klitmose

Jens Ulrik Poulsen

Jens Aage Munk

Henrik Ljunggreen

Henning Munk Ejlersen

So Slashedren Mikkelsen

Anders Heger

Jens Mo slashedller-Jensen

John Thrane Hansen

A dose setting device for a delivery system has a piston rod ( ) which successively presses a piston ( ) into a cylinder ampoule ( ). Doses are set by rotating a second part ( ) of the piston rod ( ) in relation to a first part ( ). The two parts are connected by mating threads so that the total length of the piston rod ( ) is increased proportional to the angle of rotation, and a point ( ) on the second part is moved away from a stop position fixed in relation to a housing ( ) The set dose is delivered when the point ( ) is moved back to the stop position. The first part ( ) can be axially displaced but not rotated in the housing ( ), and the second part ( ) can both rotate and be axially displaced. The first part ( ) is maintained in abutment with the piston ( ) and the second part ( ) is coupled to be rotated by a dose setting wheel ( ). An injection push button ( ) is movable between a projecting position and a pressed home position and has elements ( ) acting on the second part ( ) to press this part to its stop position.

Dose setting device

In a syringe dosing mechanism a threaded spindle (1) and a nut (3) cooperates so that relative rotation thereof moves the nut (3) along the spindle (1). The nut (3) has two intersecting bores (12, 15). The first bore (15) has an inner thread (7) matching the outer thread (2) of the spindle (1) and the second bore (12) is smooth and fits slidingly over the spindle (1). The nut (3) is tiltable between a first and a second position. In the first position the threaded bore (15) is coaxial with the spindle (1) and in the second position the smooth bore (12) is coaxial with the spindle (1). The nut (3) is at a first side hinged to a piston rod (6)so that exertion of a force by the nut (3) on the piston rod (6) in a direction (10) by which an injection is performed will tilt said nut (3) into its first position. A piston withdrawal member acts at a second side of said nut diametrically opposite said first side so that the nut (3) is tilted to its second position when the withdrawal member applies a force (13) to said nut (3).

Syringe with tiltable nut for quick piston disengagement

Displacement system for controlled infusion of a liquid

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Gilleleje, Denmark

Preben Broskov Nielsen