Neuland Laboratories Limited

Praveenkumar Neela

Ponnaiah Ravi

Batthini Guruswamy

Uppala Manikya Rao

Kashyap Ravindrabhai Wadekar

Kubireddy Vigneshwar Reddy

Sribhashyam Ravikanth

Sampath Kumar Laxmalla

The present invention provides a process for the preparation of sugammadex sodium involving the step of: reacting 6-perdeoxy-6-per-halo-gamma-cyclodextrin with 3-mercapto propionic acid in the presence of alkali metal alkoxide in an organic solvents. The invention also provides a process for purifying the sugammadex or its pharmaceutically acceptable salts using water and organic solvents.

Process for preparation of sugammadex sodium

An improved process for preparation of Olanzapine pamoate monohydrate from Olanzpaine is disclosed which comprises mixing at room temperature a solution of olanzapine prepared in water in presence of an acid, with a solution of pamoic acid prepared in water in presence of a base; stirring and maintaining the reaction mixture for a sufficient time till precipitation of solid and drying the solid to obtain olazapine pamoate monohydrate.

Process for the preparation of olanzapine pamoate

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Hyderabad Telangana, India

Praveenkumar Neela