University of Pittsburgh

Carnegie Mellon University

Changs-ascending Enterprise Co

Commonwealth System of Higher Education

Chang, Chun-chieh

Chang, Tsun-yu

Kumta, Prashant N.

Prashant Nagesh Kumta

Moni Kanchan Datta

Oleg Velikokhatnyi

Partha Saha

Abhijit Roy

Da-Tren Chou

Prashanth Jampani Hanumantha

Bharat Gattu

Charles S Sfeir

Prashanth J Hanumantha

Pavithra Murugavel Shanthi

Madhumati Ramanathan

Mitali Shirish Patil

Ayyakkannu Manivannan

Daeho Hong

Karan Sandeep Kadakia

Chun-Chieh Chang

Lee E Weiss

Shrinath Ghadge

Dae Ho Hong

Sung Jae Chung

Prasad P Patel

Ramalinga Kuruba

Tsun-Yu Chang

Phil G Campbell

Jeffrey O Hollinger

Wei Wang

Sangeetha Kunjukunju

Nicole J Ostrowski

Gary Yu

Boeun Lee

Jingyao Wu

Prashanth Hanumantha Jampani

Kacey Gribbin Marra

David Okonkwo

Jay Wynn Calvert

Vijay Saradhi Gorantla

Daiwon Chol

Daiwon Choi

Ipsita Banerjee

Thomas Richardson

Mandyam Ammanjee Sriram

Robert Kormos

Mitali Patil

Amit Paul

Mitali S Patil

Jason Smith

David M Sipe

Gregory W Fisher

The invention provides noble metal-free electro-catalyst compositions for use in acidic media, e.g., acidic electrolyte. The noble metal-free electro-catalyst compositions include non-noble metal absent of noble metal. The non-noble metal is non-noble metal oxide, and typically in the form of any configuration of a solid or hollow nano-material, e.g., nano-particles, a nanocrystalline thin film, nanorods, nanoshells, nanoflakes, nanotubes, nanoplates, nanospheres and nanowhiskers or combinations of myriad nanoscale architecture embodiments. Optionally, the noble metal-free electro-catalyst compositions include dopant, such as, but not limited to halogen. Acidic media includes oxygen reduction reaction (ORR) in proton exchange membrane (PEM) fuel cells, and direct methanol fuel cells and oxygen evolution reaction (OER) in PEM-based water electrolysis and metal air batteries, and hydrogen generation from solar energy and electricity-driven water splitting.

Highly active, robust and versatile multifunctional, fully non-noble metals based electro-catalyst compositions and methods of making for energy conversion and storage

The invention relates to lithium-based battery systems and, more particularly, to electro-spinable solution compositions, electro-spun sulfur-polymer fibers, e.g., wires and yarns, and their use in preparing high performance sulfur mattes, e.g., electrodes, for lithium-sulfur batteries with potential applications in small-scale mobile devices. The sulfur-polymer fibers have nanoscale dimensions and yarn-like morphology. The sulfur-polymer fibers can be prepared by co-dissolving sulfur and polymer in a solvent for forming the electro-spinable solution, and electrospinning the solution. The electrospun fibers can be used to form a composite that includes alternating layers of the electrospun fibers and polymer on a current collector.

Electro-spun sulfur wire for fabricating mattes of lithium sulfur batteries

The inventive concepts include at least an electrode architecture including a composite structure that includes engineered carbon nanofibers, a lithium-impervious elastic polymer, a copper collector and a lithium-containing cathode; dendrite-free, lithium metal-plated anode that includes the electrode architecture; and a lithium metal-based lithium ion battery that includes the lithium metal-plated anode, liquid and solid electrolytes and a lithium-free cathode.

Methods of fabrication of engineered carbon nanofiber/Cu electrode architectures for dendrite-free high efficiency Li metal batteries

The invention relates to biodegradable, metal alloys, methods for their preparation and applications for their use. The alloys include magnesium and other components, such as, yttrium, calcium, zirconium, and zinc. These elements are alloyed together in specific combinations and amounts in order to achieve an alloy having desired properties and characteristics. In certain embodiments, strontium or cerium may be included as an additive. The resulting alloys are particularly suitable for forming various medical devices for implantation into the body of a patient.

Properties and parameters of novel biodegradable metallic alloys

The invention relates to ex-situ biosensors that impedimetrically detect cardiac biomarkers of interest in a bodily fluid sample derived from a patient. The biosensors include a multi-array of vertically aligned platinum wires having immobilized thereon an aptamer that is selected to specifically and selectively bind to the cardiac markers of interest. The biosensors are contacted with a portion of the bodily fluid sample, and the aptamer binds to the cardiac markers of interest in the bodily fluid sample. As a result, an electrochemical impedance signal is generated and therefore, a change in electrochemical impedance is indicative of the presence of the cardiac markers of interest in the bodily fluid sample. The biosensors are point-of-care, on-demand devices that can be used in a medical environment, as well as in domestic settings.

Development and parameter assessment for vertically aligned platinum wire aptasensor arrays for impedimetric detection of cardiac biomarkers

The invention relates to Chevrel-phase materials and methods of preparing these materials utilizing a precursor approach. The Chevrel-phase materials are useful in assembling electrodes, e.g., cathodes, for use in electrochemical cells, such as rechargeable batteries. The Chevrel-phase materials have a general formula of MoZ(Z=sulfur) or MoZZ(Z=sulfur; Z=selenium), and partially cuprated CuMoSas well as partially de-cuprated CuMgMoSand the precursors have a general formula of MMoZor MMoZZ, M=Cu. The cathode containing the Chevrel-phase material in accordance with the invention can be combined with a magnesium-containing anode and an electrolyte.

Cathodes and electrolytes for rechargeable magnesium batteries and methods of manufacture

The invention, relates to flexible, thin trim batteries for use in a variety of applications including, but not limited to, flexible electronics, flexible energy storage systems, wearable textile-like energy devices and various other integrated electronic and mobile device-based applications. The flexible, thin, film batteries allow the design and development of weavable, conformable, wearable and flexible components for advanced battery technology. The invention relates to flexible energy storage system that include an electrospun, textile-like, weaved assembly including a flexible cathode, a flexible anode, and an electrolyte. The electrolyte can include a flexible gel-polymer and a nanostractured filler.

Weavable, conformable, wearable and flexible components for advanced battery technology

The invention relates to biodegradable iron alloy-containing compositions for use in preparing medical devices. In addition, biodegradable crystalline and amorphous compositions of the invention exhibit properties that make them suitable for use as medical devices for implantation into a body of a patient. The compositions include elemental iron and one or more elements selected from manganese, magnesium, zirconium, zinc and calcium. The compositions can be prepared using a high energy milling technique. The resulting compositions and the devices formed therefrom are useful in various surgical procedures, such as but not limited to orthopedic, craniofacial and cardiovascular.

Biodegradable iron-containing compositions, methods of preparing and applications therefor

The invention includes an ex-situ biosensors that impedimetrically detect one or more target biomarkers of brain injury or disease in a bodily fluid sample derived from a patient. The biosensors include a multi-array of vertically aligned platinum wires having immobilized thereon antibody and/or aptamer that specifically and selectively bind to the one or more target biomarkers. An electrochemical impedance signal is generated, and a change in electrochemical impedance is indicative of the presence of the one or more target biomarker(s) in the bodily fluid sample. The biosensors are point-of-care, on-demand devices useful in a medical and domestic environment.

Multi-array impedimetric biosensors for the detection of concussion and traumatic brain injuries

The invention relates to polyelectrolyte multilayer coatings and, methods for their preparation and application to substrates to enhance the bioactivity and corrosion protection of the substrates' surface. The invention is particularly suitable for coating substrates employed for medical applications, such as but not limited to medical implant devices for drug and/or biologics delivery in a patient. The substrate has a positive or negative charge. The polyelectrolyte multilayer coatings include at least a first polymer layer and a second polymer layer. The first polymer and second polymer have opposite charges. Each of the polymer layers is individually applied using a layer-by-layer such that an alternating charge multilayer coating is formed.

PEM layer-by-layer systems for coating substrates to improve bioactivity and biomolecule delivery

The invention includes compositions including magnesium-lithium alloys containing various alloying elements for medical implant devices. The devices are constructed of the compositions or have applied thereto a coating formed therefrom. Within the structure of the magnesium-lithium alloy, there is a co-existence of alpha and beta phases. The invention also includes methods of preparing the magnesium-lithium alloys and articles, such as medical implant devices, for use in medical applications, including orthopedic, dental, craniofacial and cardiovascular surgery.

Ultrahigh ductility, novel Mg—Li based alloys for biomedical applications

The invention relates to lithium ion batteries and, more particularly, to lithium ion conducting composite polymer electrolyte separators. The separators include a nanofiber mat composed of electrospun nanofibers. The nanofibers include a polymer having one or more polar halogen groups, a lithium-containing solid or liquid electrolyte and nanoparticle filler. The polymer, electrolyte and filler are combined to form a solution that is subjected to the electro-spinning process to produce electrospun nanofibers in the form of the mat.

Electrospinning of PVdF-HFP: novel composite polymer electrolytes (CPES) with enhanced ionic conductivities for lithium-sulfur batteries

The invention relates to biodegradable, magnesium alloys, compositions and composites, methods for their preparation and applications for their use as implantable medical devices in load-bearing conditions. The magnesium alloys are composed of alloying elements selected from yttrium, calcium, zirconium, zinc, and strontium, with the remainder being magnesium and impurities due to production, and are prepared by melting together the elements and casting the resulting melted mixture. In certain embodiments, the methods of preparation include solution treatment and hot extrusion.

Degradable magnesium-based implant devices for bone fixation

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Pittsburgh, PA, United States of America

Prashant Nagesh Kumta