Glenmark Pharmaceuticals S.a.

Prashant Dilip Wadekar

Neelima Khairatkar-Joshi

Abraham Thomas

Daisy Manish Shah

Sachin Sundarlal Chaudhari

Malini Bajpai

Sanjib Das

Shailesh Ramesh Pardeshi

Vishal Govindrao Deshmukh

The present disclosure is directed to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein X, X, M, R, R, R, R, m, n, and p are as defined herein, which are active as modulators of retinoid-related orphan receptor gamma t (ROR&#x3b3;t). These compounds prevent, inhibit, or suppress the action of ROR&#x3b3;t and are therefore useful in the treatment of ROR&#x3b3;t mediated diseases, disorders, syndromes or conditions such as, e.g., pain, inflammation, COPD, asthma, rheumatoid arthritis, colitis, multiple sclerosis, neurodegenerative diseases and cancer. 

Bicyclic heteroaryl indole analogues useful as ROR gamma modulators

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Maharashtra, India

Prashant Dilip Wadekar