King Fahd University of Petroleum and Minerals

Pran Kishore Deb

Katharigatta N Venugopala

Mohamed A Morsy

Bandar Aldhubiab

Sandeep Chandrashekharappa

Mahesh Attimarad

Anroop B Nair

Nagaraja Sreeharsha

Christophe Tratrat

Melendran Pillay

Vijaykumar Uppar

Sheena Shashikanth

Basavaraj Padmashali

Raghu Prasad Mailavaram

Viresh Mohanlall

Dhakshanamurthy Thirumalai

Madhusudana Reddy Muthukurpalya Bhojegowd

Ramasamy Durai

Melandran Pillay

Compounds for treating tuberculosis and, particularly, to anti-tubercular compounds that are substituted 1,4-dihydropyrmidines and their use as anti-tubercular agents.

Substituted 1,4-dihydropyrimidines as antitubercular agents

Compounds for treating tuberculosis and, particularly, antitubercular compounds that are 1-substituted benzoyl-4-bromopyrrolo[1,2-a]quinoline-3-carboxylate derivatives and their use as antitubercular agents are provided.

1-substituted benzoyl-4-bromopyrrolo[1,2-a]quinoline-3-carboxylate derivatives as antitubercular agents

The substituted indolizine dicarboxylates are antibacterial agents. The emergence of drug-resistant bacteria calls for constant development of new antibacterial agents with the aim of generating medicaments that are potent against drug sensitive and resistant bacteria and are well tolerated. The present compounds are not only new, but have very valuable antimicrobial properties. These compounds showed a broad spectrum of activity against tuberculosis mycobacteria. Based on their pharmacological profiles, the present compounds may find important clinical applications for severe infectious diseases and tuberculosis.

7-isopropyl 1-ethyl/methyl 3-(substituted benzoyl)-2-substituted indolizine-1,7-dicarboxylates as anti-tubercular agents

Growing community of inventors

Amman, Jordan

Pran Kishore Deb