Piramal Enterprises Limited

Pramod Bhaskar Kumar

Rajiv Sharma

Sanjay Kumar

Ram Asrey Vishwakarma

Somesh Sharma

Sivaramakrishnan Hariharan

Vijaykumar Bhagwan Deore

Hitesh Mistry

Nilesh Dagia

Bichismita Sahu

Mandar Bhonde

Deepak Singh

Mahesh Dawange

Sunil Vasantrao Mali

Pallavi Hanmantrao Mane

Ramswaroop Mundada

The present invention relates to a compound of formula I, or an isotopic form, stereoisomer, a tautomer, a pharmaceutically acceptable salt, a solvate, a polymorph, a prodrug, N-oxide or S-oxide thereof; and processes for their preparation. The invention further relates to pharmaceutical compositions containing the compounds and their use in the treatment of diseases or disorders mediated by ROR&#x3b3;.

ROR-gamma modulators and uses thereof

The present invention relates to compounds of formula (I), wherein R, R, R, R, Rand Rare as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases mediated by phosphatidylinositol-3-kinase (PI3K), mammalian target of rapamycin (mTOR), Signal transducer and activator of transcription 3 (STAT 3), tumor necrosis factor-&#x3b1; (TNF-&#x3b1;), interleukin-6 (IL-6) or a combination thereof particularly in the treatment of cancer and inflammation.

Imidazopyridine derivatives

The present invention provides the compounds of formula (I): The present invention relates to imidazo[4,5-c]quinoline derivatives of formula (I), process for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases mediated by phosphatidylinositol-3-kinase (PBK) and/or mammalian target of rapamycin (mTOR) and/or tumor necrosis factor-&#x3b1; (TNF-oc) and/or interleukin-6 (IL-6), particularly in the treatment of cancer and inflammation.

Imidazo [4,5-C]quinoline derivatives and their use in the treatment of tumors and/or inflammation

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Mumbai, India

Pramod Bhaskar Kumar