Medimmune Limited

Prakash Manikwar

Changshou Gao

Scott A Hammond

Claire Louise Dobson

Ronald Herbst

Darren Schofield

Godfrey Rainey

Stacey Drabic

Michelle Morrow

Yariv Mazor

Srinath Kasturirangan

Brian Lobo

Michael Oberst

Gianluca Carlesso

Jonathan Seaman

Simon Dovedi

Kristen Pollizzi

Emma Suzanne Cohen

Catherine Eugenie Chaillan Huntington

Roland Wilhelm Kolbeck

Susan Hoe

Kellisa Beth Hansen

Saba Ghazvini

Dexter Joseph D'sa

David Lechuga-Ballesteros

The present technology relates generally to dry powder formulations of antibodies specific for thymic stromal lymphopoietin (TSLP), as well as methods of treating asthma, using the dry powder formulations, suitably via pulmonary delivery.

Dry powder formulations of thymic stromal lymphopoietin (TSLP)-binding antibodies and methods of use thereof

The disclosure generally provides proteins that bind two epitopes (e.g., a first and a second epitope) and that are bivalent for binding to each of the first and second epitopes. The disclosure also provides for specific binding proteins, including antibodies, which bind to a target protein. The disclosure also provides compositions comprising such proteins, nucleic acid molecules encoding such proteins and methods of making such proteins. The disclosure provides methods of inducing an immune response in a subject as well as methods for treating or preventing cancer in a subject by administering the proteins, nucleic acid molecules and/or compositions to the subject.

Bispecific binding proteins and uses thereof

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Gaithersburg, MD, United States of America

Prakash Manikwar