Other

Virginia Tech Intellectual Properties Inc

Inotek Pharmaceuticals Corporation

Prakash G Jagtap

John F Kadow

John Henry Van Duzer

Erkan Baloglu

Andrew L Salzman

Csaba Szabo

Mahendra Devichand Chordia

David G Kingston

David George Ian Kingston

2-debenzoyl-4-deacetyl paclitaxel, antineoplastic analogs thereof and intermediates are taught, as well as the formation of the compound, analogs and intermediates. The compound, analogs and intermediates may be used to form pharmaceutical compositions having anti-neoplastic activity. Further, the compound, analogs and intermediates may be used to treat cancer when applied in an effective amount by means such as a pharmaceutical composition.

2-aroyl-4-acyl paclitaxel (Taxol) analogs

The present invention provides methods for making a novel class of 1-deoxy paclitaxel derivatives. These derivatives include 1-deoxy paclitaxel. The derivatives of the present invention are potent cytotoxic agents.

Methods for preparing 1-deoxy paclitaxels

Growing community of inventors

Blacksburg, VA, United States of America

Prakash G Jagtap