Bristol-myers Squibb Pharma Company

E.i. Dupont De Nemours and Company

Dupont Pharmaceuticals Company

Prahlad R Singh

Milind Rajopadhye

Shuang Liu

Thomas David Harris

Alan P Carpenter, Jr

John A Barrett

D Scott Edwards

Stuart J Heminway

Gerald P Tercho

Robert E Lewis

Jack N Wentz

Joseph Glajch

Keith R Olewine

Paul R Walsh

Pharmaceuticals for the imaging of angiogenic disorders

Radiotherapy agents which are solid or porous particles are described. The particles are of an inorganic material containing a suitable radionuclide and having an average particle diameter of about 0.05 to 5000 microns.

Inorganic materials for radioactive drug delivery

Novel radioactive seeds for brachytherapy and a reproducible method of manufacturing the seeds is described, wherein the seeds contain either Pd-103 or I-125 disposed within a cured resin matrix.

Radioactive seeds for brachytherapy and a process for making the same

An intra-coronary radiation devices containing Ce-144 or Ru-106 deposited onto a wire and coated with a biocompatible material and methods of making and using the same.

Intra-coronary radiation devices containing Ce-144 or Ru-106

The present invention describes novel radiopharmaceuticals of formula (I): ##STR1## wherein J, K, L, and M, are amino acids or derivatives thereof and R', R.sup.1, R.sup.2 and n are as defined herein, that are radiolabeled cyclic compounds containing chelators which act as antagonists of the platelet glycoprotein IIb/IIIa complex, methods of using the same as imaging agents for the diagnosis of arterial and venous thrombi, and novel reagents for the preparation of the same and kits comprising the reagents.

Technetium-99m labeled chelator incorporated cyclic peptides that bind

Growing community of inventors

Arlington, MA, United States of America

Prahlad R Singh