Akamara Therapeutics, Inc.

Ankara Therapeutics, Inc.

Pradip Dutta

Arindam Sarkar

Shiladitya Sengupta

Monideepa Roy

Aniruddha Sengupta

Sk Samad Hossain

Aasif Ansari

Nimish Gupta

Swadhin K Mandal

Heeralal Bassi

The present invention is in relation to the fields of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to improved methods for preparing lipid-conjugated platinum compounds with high purity and good yields. The present disclosure also relates to nanoparticles comprising lipid-conjugated platinum compounds with high drug loading efficiency for use in chemotherapy, and to methods for producing said nanoparticles.

Process for preparing supramolecular platinum-based compounds

The present disclosure is in relation to the field of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to platinum based compounds comprising platinum moiety, linker moiety and lipid moiety and corresponding nanoparticles thereof. The disclosure further relates to synthesis of said platinum based compounds, nanoparticles and compositions comprising said platinum based compounds/nanoparticles. The disclosure also relates to methods of managing cancer by employing aforesaid carbene compounds, platinum based compounds, nanoparticles and compositions thereof.

Lipid-based platinum compounds and nanoparticles

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New Delhi, India

Pradip Dutta