Daiichi Sankyo Company, Limited

Pradip Balu Wagh

Rie Miyauchi

Masatoshi Nagamochi

Shin Iimura

Sunanda Ghosh Dastidar

Ashwani Kumar Verma

Masayuki Ishizaki

Punit Kumar Srivastava

Kumaragurubaran Nagaswamy

Soma Ghosh

Balkrishna Ramchandra Kale

Aniruddha Mondal

Rijwan Jaffer Momin

Sonali Nanasaheb Pansare

Pramod Raosaheb Markad

Yogesh Balasaheb Khairnar

Takeshi Murata

Lalima Sharma

The present invention provides a heterocyclic compound of formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof or a hydrate thereof, wherein A, A' B, D, R, Rand Rare as defined herein, a pharmaceutical composition comprising a compound of formula (I) as an active ingredient, methods of production, and methods of use thereof. Particularly, the present invention provides a compound of formula (I) useful for treating or preventing a disease, condition or disorder associated with protein kinases, preferably Janus Kinase family.

Heterocyclic compounds as protein kinase inhibitors

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Nashik, India

Pradip Balu Wagh