Cempra Pharmaceuticals, Inc.

Prabhavathi Fernandes

David Eugene Pereira

Sara Wu

Pharmaceutical compositions adapted for the parenteral administration, including intravenous administration, of triazole containing macrolide antibiotics, and methods for their use in the treatment of bacterial, protozoal, and other infections are described herein.

Parenteral formulations for administering macrolide antibiotics

Described herein are compounds and pharmaceutical compositions useful for treating inflammatory diseases.

Compounds and methods for treating inflammatory diseases

Described herein are macrolide and ketolide antibiotics and pharmaceutical compositions, methods, and uses thereof for treating diseases caused at least in party by resistant bacteria.

Methods for treating resistant diseases using triazole containing macrolides

Compounds of formula (I), compositions comprising them, and methods and uses thereof are described herein for the treatment of respiratory diseases, including cystic fibrosis. Inhalation formulations of macrolide antibiotics are also described herein. The treatment of bacterial infections continues to be an important endeavor of pharmaceutical research and development. The specter of bacterial resistance to currently available antibiotics is ever-present, and accordingly, new and improved compounds, pharmaceuticals formulations, treatment methods, and treatment protocols are needed. 

Methods for treating respiratory diseases and formulations therefor

Use of macrolide and ketolide antibiotics for the treatment of acute exposure and diseases caused by biodefense pathogens is described.

Biodefenses using triazole-containing macrolides

Described herein are formulations and methods for treating diseases caused by infectious pathogens, includingcomplex,, Nocardia,, and

Methods for treating malaria, tuberculosis and MAC diseases

Described herein are macrolide and ketolide antibiotics and pharmaceutical compositions, methods, and uses thereof for treating gastrointestinal diseases.

Methods for treating gastrointestinal diseases

Triazole-containing macrolide and ketolide antibiotics, therapeutic compositions containing them and methods of use for treating diseases caused by one or more resistant organisms are described.

Methods for the treatment and prevention of a bacterial infection caused by, or, or bothand, such as urethritis, an ocular infection, or a pharyngeal infection, using fusidic acid, or pharmaceutically acceptable salt thereof, are described.

Growing community of inventors

Chapel Hill, NC, United States of America

Prabhavathi Fernandes