University of California

Pooja C Patel

Jogeshwar Mukherjee

Elizabeth Head

Crystal Wang

Compounds, compositions and methods are contemplated in which senile plaques and/or neurofibrillary tangles are labeled using compounds with improved permeability across the blood brain barrier and improved selective binding to senile plaques and/or neurofibrillary tangles. Contemplated compounds are derivatives of FDDNP or curcumin, which most preferably have improved solubility in aqueous solvents. Labeling is typically performed using a PET detectable label, and especiallyC andF.

Growing community of inventors

Stockton, CA, United States of America

Pooja C Patel