The Chinese University of Hong Kong

Hong Kong Jockey Club Institute of Chinese Medicine Limited

Po Ming Hon

Hui Dong

Ge Lin

Paul P H But

Pui-Hay Paul But

Ren Wang Jiang

Pang Chui Shaw

Yan-Tong Xu

Hoi Sing Chung

Method for relieving cough using an effective antitussive chemical compound belonging to stemoamide or tuberostemospironine and method for manufacturing pharmaceutical compositions for treating or relieving cough in human and animal subjects which including a stemoamide or tuberostemospironine compound. In addition, the antitussive property of the compounds provides a method for assessing the quality of herbs traditionally used in treating cough by analyzing the content of the effective chemical ingredient, i.e., compounds of stemoamide type and/or tuterostemospironine type. It further provides a method for identifying medicinal herbs which may be used for relieving cough by phytochemical determination of the existence of compounds that are of stemoamide or tuterostemospironine type.

Method of making antitussive medicine and relieving cough

The present invention provides plant extracts, isolated alkaloids, synthetic alkaloids and compositions having antitussive activity. In some preferred embodiments, the plant extracts and the isolated alkaloids are from a plant of a genus in the familyIn other preferred embodiments, the plant extracts and the isolated alkaloids are from a plant of the genusorIn especially preferred embodiments, the plant extracts and the isolated alkaloids are from the plantThe present invention further provides methods for isolating such plant extracts and alkaloids. In addition, the present invention provides methods for reducing or suppressing coughing by administering plant extracts, alkaloids and compositions having antitussive activity.

Plant extracts and alkaloids having antitussive activity

Growing community of inventors

Hong Kong, China

Po Ming Hon