Roche Molecular Systems, Inc.

Leister Process Technologies

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Pius Studer

Thomas Schlaubitz

Daniel Bommer

Leo Wallimann-Durrer

Lukas Gisler-Reinhard

A heating device for heating a thermally fixable sealing cover disposed over the microplate adjacent the wells, a cooling device for actively cooling the microplate and a controller set up to control activity of the heating and cooling devices in a manner to heat the sealing cover so as to thermally fix it to the microplate and to actively cool the microplate so as to keep a temperature of the samples below a predefined temperature when heating the sealing cover. It further relates to a method for automatically sealing a microplate in which the thermally fusible sealing cover is disposed over the microplate, the sealing cover is heated to thermally fix it to the microplate and the microplate is actively cooled in a manner that a temperature of the liquid reaction mixtures is kept below a predefined temperature when heating the sealing cover.

Instrument and method for automatically heat-sealing a microplate

An air heater is provided with a connecting case for the power supply and the air to be heated, as well as a heating element attached to the connecting case by means of a carrier. In the connecting housing, the carrier is connected via a plug connection with the connection board for transmitting the heating current. For this purpose, a receptacle angle bracket is provided that can be inserted into the connecting housing and locked in place. The receptacle angle bracket has cylindrical sleeves serving as electrically insulating bushings for the contact pins on the carrier. In order to tap reference voltages for the control device, the contact pins of the plug connection can be connected with the contact tracks of the connection board of the control device by means of rubber-elastic conductive connecting elements. In order to establish the contact, an injection-molded part made of conductive rubber is used that is pressed against the contact points when the connection board is installed in the connecting housing. The air heater is distinguished by its small number of individual components that allow its quick assembly.

Air heater

Growing community of inventors

Lucerne, Switzerland

Pius Studer