Glycom A/s

Carbocode S.a.

Piroska Kovács-Pénzes

Gyula Dekany

Markus Jondelius Hederos

Markus Hederos

Lars Kröger

Andreas Schroven

Christoph Röhrig

Julien Boutet

Ioannis Vrasidas

Christian Risinger

Ferenc Horváth

Károly Ágoston

Ágnes Ágoston

István Bajza

Gergely Pipa

Sándor Demkó

Ignacio Pérez Figueroa

Péter Trinka

Johan Olsson

Gyula Dékany

Istvan Bajza

Jorge Santos

Ignacio Figueroa Pérez

László Kalmár

Andras Nagy

Györgyi Osztrovszky

Elise Champion

Marie Bøjstrup

Mette Fanefjord

Ignacio Figueroa-Pérez

Gábor Kádár

Sándor Demkò

Krisztián Kovàcs

Ferenc Horvàth

Ágnes Jànosi

Irme Kovács

Ignacio Figuero-Pérez

Imre Kovács

Gyula DÉKANY

The present invention relates to sphingolipids, a method for the production of sphingoid bases, especially sphingosine, and novel derivatives thereof. The sphingoid bases are herein produced by making use of a vinylogous amide-type protecting group. The resulting vinylogous amide compounds enable an easy and effective production of sphingoid bases, especially sphingosine.

Sphingosine/sphingoid base production

The present invention relates to several novel 1-O-glycosylated sphingoid bases and to a production method thereof, as well as to uses of the 1-O-glycosylated sphingoid bases. Sphingoid bases carrying a vinylogous amide-type protecting group are used herein for the production of 1-O-glycosylated sphingoid bases. These vinylogous amide compounds enable an easy and effective production of 1-O-glycosylated sphingoid bases.

Glycosylated sphingoid bases and production thereof

The present invention relates to a method for preparation of the trisaccharide 6'-O-sialyllactose (formula (I)) or salts thereof as well as intermediates in the synthesis and for the use of 6&#x2032;-O-sialyllactose salts in pharmaceutical or nutritional compositions. 

Production of 6'-O-sialyllactose and intermediates

The invention relates to a method for the synthesis of compounds of general formula (1A) and salts thereof wherein one of the R groups is an &#x3b1;-sialyl moiety and the other is H, Xrepresents a carbohydrate linker, A is a D-glucopyranosyl unit optionally substituted with fucosyl, Ris a protecting group that is removable by hydrogenolysis, the integer m is 0 or 1, by a transsialidation reaction.

Synthesis of sialooligosaccharide derivatives

The present invention relates to an improved synthesis of a trisaccharide of the formula (1), novel intermediates used in the synthesis and the preparation of the intermediates. 

Method for the synthesis of a trisaccharide

The present invention relates to a method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt, formula (I)) especially in large scale, as well as intermediates in the synthesis, a new crystal form (polymorph) of LNnt, and the use thereof in pharmaceutical or nutritional compositions. 

Method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt) containing N-acetyllactosamine

The present invention relates to an improved synthesis of a trisaccharide of the formula, novel intermediates used in the synthesis and the preparation of the intermediates. 

The present application discloses a method for the crystallization of fucose, characterized in that the crystallization is carried out from a mixture comprising fucose and at least one 6-deoxy sugar selected from 6-deoxy-talose and 6-deoxy-gulose. In one embodiment, the mixture comprises fucose and 6-deoxy-talose.

Method for crystallization of fucose

The present invention relates to novel polymorphs of the trisaccharide 2'-O-fucosyllactose (2-FL) of formula (1), methods for producing said polymorphs and their use in pharmaceutical or nutritional compositions. 

Polymorphs of 2'-O-fucosyllactose and producing thereof

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Jászberény, Hungary

Piroska Kovács-Pénzes