Agency for Science, Technology and Research

Ping Bai

Xiaodong Zhou

Lin Wu

Hong Yan Song

Anton Sadovoy

Ten It Wong

Mingxia Gu

Erping Li

There is method for detecting the presence or absence of a target analyte in a sample comprising the steps of: allowing an inorganic fluorescent particle to conjugate with a detection biomolecule that is bound to said target analyte, if present in said sample, said target analyte additionally being bound by a capture biomolecule immobilized on or within a nanostructure; and detecting the fluorescence emitted by said inorganic fluorescent particle, said nanostructure being capable of generating a surface plasmon resonance effect when excited by a light source to substantially increase the fluorescence emitted by said inorganic fluorescent particle, wherein the detected fluorescence indicates the presence of said target analyte in said sample.

Method for detecting a target analyte

A plasmonic detector and method for manufacturing a plasmonic detector. The plasmonic detector comprises two nanoscale metallic rods coupled to a bias voltage; a nanoscale cavity formed between adjacent ends of the two nanoscale metallic rods; and an absorption material disposed in the nanoscale cavity for converting an electromagnetic field to an electric current for outputting via the nanoscale metallic rods.

Plasmonic detector and method for manufacturing the same

A sensor and a method of detecting a target analyte are provided. The sensor includes a substrate; a layer comprising a plurality of through holes, wherein the layer is disposed above the substrate; a first element configured to detect a target analyte; a second element that can produce a detectable signal; wherein the first element and the second element are configured to couple the target analyte between the first element and the second element.

Sensor and method of detecting a target analyte

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Singapore, Singapore

Ping Bai