Bigtec Private Limited

Vittal Mallya Scientific Research Foundation

Vittal Mallya Scientific Research

Pillarisetti Venkata Subbarao

Chandrasekhar Bhaskaran Nair

Phani Kumar Pullela

Mulakkapurath Narayanan Manoj

Sathyadeep Viswanathan

Renjith Mahiladevi Radhakrishnan

Raviprakash Jayaraman

Kirubakaran Naveen Kumar

Madhuri Baliga

Venkata Ramachandra Rao Vasamsetty

Kishore Krishna Kumar

Jeffrey A Bibbs

Sudip Mondal

Srinivasa Rao Alapati

Paramashivappa Rangappa

Shilpa Chennakrishnaiah

Manjula Jagannath

Sankaranand Kaipa Narasimha

Venkatakrishnan Venkataraman

Gopalakrishna Mangalore Kini

Santhosh Kumar Gandhavalla

Mitchell Preetham Pinto

Phanikumar Pullela

Gopalkrishna Mangalore Kini

Venkataraman Venkatakrishnan

Swetha Chandra

The present disclosure provides a non-contact real time micro Polymerase Chain Reaction (PCR) system comprising; a chip having a reaction chamber for holding a sample and an embedded metal heater below the reaction chamber for heating the sample; an optical unit comprising an associated LED driver and a photo detector amplifier placed above the chip to detect fluorescence; an induction heater mounted around the chip and inductively coupled to the metal heater; an infrared temperature sensor mounted below the chip for measuring a temperature of the metal heater, wherein the infrared temperature sensor is interfaced with a signal conditioner; and a controller interfaced with the signal conditioner and the induction heater for regulating the power to the induction heater based on feedback received from the infrared temperature sensor through the signal conditioner.

Non contact real time micro polymerase chain reaction system and method thereof

Instant invention is about a hand held micro PCR device comprising a LTCC micro PCR chip comprising a heater, a reaction chamber to load a sample. It also comprises a heater control to regulate the heater on basis of input received from a temperature sensor. It further has an optical system having an optical fiber to detect a fluorescence signal from the sample, and at least one communication interface to interact with other device(s).

Hand held micro PCR device including microcontroller for exchanging information with a communications interface

In one aspect, methods relate to the field of recombinant DNA therapeutics. Methods may involve bio-informatics design, synthesis of artificial genes for a human insulin precursor having a leader peptide coding sequence, cloning artificial genes into an expression vector, and expression in an organism such as one selected from the genus. In another aspect, methods may include downstream processing for obtaining protein precursor molecules and subsequent conversion of protein precursor molecules to functional proteins.

Method of downstream processing for conversion of human insulin precursor molecule into a functional human insulin protein molecule

Polynucleotide and polypeptide sequence and methods thereof

The present invention relates to a biofuel composition comprising normal chain alcohol(s), natural oils and diesel optionally along with fuel additive(s); a process of preparation and a method of fueling said biofuel composition.

Biofuel composition, process of preparation and a method of fueling thereof

Instant invention is about a micro chip comprising plurality of layers of LTCC wherein a reaction chamber is formed in plurality of top layers to load samples. A heater embedded in at least one of the layers below the reaction chamber and a temperature sensor is embedded in at least one of the layers between the heater and the reaction chamber for analyzing the sample. The temperature sensor can be placed outside the chip to measure the chip temperature.

Micro chip

The present disclosure provides a method to isolate natural & artificial nucleic acids like deoxyribonucleic acid (DNA), ribonucleic acid (RNA) and peptide nucleic acid (PNA) from a solid or liquid sample using cotton. The cotton packed is such that, a solution containing nucleic acids passes through it and the nucleic acids in solution are bound to the cotton in a medium optimal for binding. The nucleic acids are bound to cotton in such a way that, the bound nucleic acids can withstand multiple washes with liquid comprising water and gets eluted in an aqueous buffer, with which eluted nucleic acids can be directly used for amplification using PCR or for any other biochemical or molecular biology needs.

Method for isolation of nucleic acids and a kit thereof

The present disclosure relates to a field of recombinant DNA therapeutics. It involves the bio-informatics design, synthesis of artificial gene for human insulin precursor including leader peptide coding sequence, cloning in an expression vector and expression in an organism, preferably. The present disclosure also relates to methods of downstream processing for obtaining protein precursor molecules and subsequent conversion of precursor molecules to functional proteins.

The present invention relates to a biofuel composition comprising distilled technical cashew nut shell liquid (DT-CNSL) and atleast one petroleum product optionally alongwith plant oils and fuel additive(s). It also relates to a process for preparation of biofuel composition and a method of fueling biofuel composition.

The present invention is directed in part towards methods of modulating the function of calcium channels with pyridine- or 1,4-dihydropyridine-based compounds. In addition, the invention describes methods of preventing and treating protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to pyridine- or 1,4-dihydropyridine-based compounds and pharmaceutical compositions comprising these compounds.

1,4-dihydropyridine and pyridine compounds as calcium channel blockers

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Karnataka, India

Pillarisetti Venkata Subbarao