Danisco US Inc.

Pilar Tijerina

Christopher James Murray

David Aaron Estell

Yiyou Chen

Giselle G Janssen

Franciscus J C Van Gastel

Franciscus Van Gastel

Franciscus JC Van Gastel

A selective targeting method is disclosed comprising contacting a library of ligands, particularly a peptide library, with an anti-target to allow the ligands to bind to the anti-target; separating the non-binding ligands from the anti-target bound ligands, contacting the non-binding anti-target ligands with a target allowing the unbound ligands to bind with the target to form a target-bound ligand complex; separating the target-bound ligand complex from ligands which do not bind to the target, and identifying the target-bound ligands on the target-bound ligand complex wherein the target-bound ligands have a Kin the range of about 10to 10M. Additionally claimed are the ligands identified according to the method.

Methods for selective targeting

The present application relates to peptides which bind to tannin, polyphenolic or anthocyanin compounds, and particularly to tea and wine stains on a fabric or other surface. The invention also concerns binding peptide conjugates which includes a binding peptide coupled to an agent and the use of the binding peptide conjugate for delivering an agent to a desired target.

Phenolic binding peptides

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San Diego, CA, United States of America

Pilar Tijerina