Unversität Zürich

Pietro Gozzoli

Boaz Harari

Andrea Guidotti

Francesco Maisano

Georgios Stefopoulos

Luca Vicentini

Monica Tocchi

An occlusion device is provided for occluding a left atrial appendage (LAA), including a compliant balloon defining a fluid-tight balloon chamber. An actuating shaft is disposed at least partially within the balloon chamber, and configured to set a distance between distal and proximal end portions of the balloon. A locking mechanism is configured to assume locked and unlocked states, and is configured, when in the locked state, to maintain, between the distal and the proximal end portions of the balloon, the distance set using the actuating shaft. The occlusion device is shaped so as to define a fluid flow path along a portion of the actuating shaft. A valve is configured to selectively allow or block fluid flow between the fluid flow path and the balloon chamber when the valve is in open and closed states, respectively. Other embodiments are also described.

Left atrial appendage occlusion devices

An occlusion device () is provided for occluding a left atrial appendage (LAA), including a compliant balloon () defining a fluid-tight balloon chamber (), and an actuating shaft (), which is disposed at least partially within the balloon chamber () for setting a distance between distal and proximal end portions () of the balloon (). A proximal LAA-orifice cover () includes a frame () and a covering () fixed to the frame (). An orifice-support stent () is fixed to and extends distally from the proximal LAA-orifice cover (), and is generally cylindrical when in a radially-expanded state. Other embodiments are also described.

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Zürich, Switzerland

Pietro Gozzoli