Danisco US Inc.

Gist-brocades N.v.

Genencor International, Inc.

Dsm N.v.

Pieter Van Solingen

Frits Goedegebuur

Martijn Scheffers

Michael C Ward

Jayarama K Shetty

Pamela K Foreman

Gang Duan

Kathy Qian

Bertus Pieter Koekman

Annemarie Eveline Veenstra

Richard Ray Bott

Brian E Jones

Wilhelmus J Quax

Wolfgang Aehle

Roberta L Farrell

Diane P Williams

Roelof Ary Bovenberg

Juan F Martin

Sara Iverson

Adrianus Wilhelmus Vollebregt

Casper Willem Vroemen

Lucia Helena Van Der Voort

Jose Luis Barredo

Rudolf Franciscus Van Beckhoven

Christina Esmahan

Martinus A Groenen

Emilio Alvarez

Bruno Diez

Santiago Gutierrez

Martien A Groenen

Wilhelmina Theresia Herbes

Wilhelmus Antonius Van Der Kleij

Margaretha Adriana Herwijer

Martien Am Groenen

Martinus Am Groenen

Annemarie E Veenstra

Lucia Hm Van Der Voort

Bertus P Koekam

Santiago Giuterrez

Jose L Barredo

The present disclosure relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present disclosure provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions and cleaning compositions. The disclosure also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.

Glucoamylase variants with altered properties

A maltogenic a-amylase from(TrAA) and variants thereof are useful in the production of high-maltose syrups from liquefied starch. Particularly high maltose concentrations are achieved when TrAA is used in the presence of a pullulanase. Expression hosts and encoding nucleic acids useful for producing TrAA and its variants also are provided.

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A maltogenic &#x3b1;-amylase from(TrAA) and variants thereof in the presence of a glucoamylase are useful in the production of high-glucose syrups from liquefied starch, where the high-glucose syrups produced thereby contain at least about 97% glucose. In this process, TrAA advantageously suppresses the reversion of glucose to malto-oligosaccharides. Expression hosts and encoding nucleic acids useful for producing TrAA and its variants also are provided.

Described herein are novel gene sequences isolated from. Two genes encoding proteins comprising a cellulose binding domain, one encoding an arabionfuranosidase and one encoding an acetylxylanesterase are described. The sequences, CIP1 and CIP2, contain a cellulose binding domain. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.

Trichoderma genes

CIP1 polypeptides and their uses

Described herein are novel gene sequences isolated from. Two genes encoding proteins comprising a cellulose binding domain, one encoding an arabionfuranosidase and one encoding an acetylxylanesterase are described. The sequences, CIP1 and CIP2, contain a cellulose binding domain. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry. 

Isolated polypeptide having arabinofuranosidase activity

Alkalitolerant xylanases

Alkaline cellulase and method of producing same

A gene expression system and a protein secretion system for eukaryotic, especially fungal, microorganisms has been provided for.

DNA comprising regulatory regions from gene y of penicillium chrysogenum

Clustered antibiotic biosynthetic genes are employed for improvement of production of the antibiotic in microorganisms and for the isolation of other genes involved in the biosynthesis of the antibiotic. The invention is exemplified with improved production of penicillin in Penicillium chrysogenum, with the isolation of another clustered biosynthetic gene(s) and with the expression of penicillin biosynthetic genes in Acremonium chrysogenum.

Method and compositions for enhancing production of secondary

Novel methods and compositions are provided for the enhanced production of secondary metabolites. Methods are provided for identifying sequences which when transformed into secondary metabolite producing hosts, enhance the production of secondary metabolite. The process is exemplified for penicillin. In addition, the P. chrysogenum acyltransferase gene is isolated and sequenced.

Method for identifying and using biosynthetic genes for enhanced

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Naaldwijk, Netherlands

Pieter Van Solingen