Université De Nantes

Institut National De La Sante Et De La Recherche Medicale

Chu Nantes

Centre National De La Recherche Scientifique

Other

Institut Francais De Recherche Pour L'exploitation De La Mer (ifremer)

Graftys

Ecole Nationale Veterinaire

Institut Francais De Recherche Pour L'exploitation De La Mer

Inserm

Pierre Weiss

Jérôme Guicheux

Guy Daculsi

Patricia Lemarchand

Jean-Michel Bouler

Corinne Sinquin

Sylvia Colliec-Jouault

Ibrahim Khairoun

Jacqueline Ratiskol

Gaël Grimandi

Eva Mathieu

Gildas Rethore

Joel Delecrin

Mathilde Mosser

Emile Rederstorff

Apolline Salama

Samia Laib

Anne Moure

Claire Vinatier

Xavier Leveque

Norbert Passuti

Francedillaois Guerin

Cécile Boyer

Anne Dupraz

Mieczyslam Lapkowski

David Riochet

Jean-Marie Bach

Emilie Rederstorff

Christophe Merceron

Jérome Guicheux

The present invention relates to the use of insulin-producing cells encapsulated in silanized hydroxypropyl methylcellulose (Si-HPMC) for the treatment of type 1 diabetes. Methods and kits are also provided for restoring and/or maintaining euglycemia in type 1 diabetic patients and in type 1 prediabetic patients.

Si-HPMC-encapsulated insulin-producing cells for the treatment of type 1 diabetes

The present invention relates to the use of an hydrogel comprising silylated biomolecule for the three-dimensional culture of cardiomyocytes or stem cells which are able to differentiate into cardiomyocytes, and to an aqueous composition comprising i) cardiomyocytes or stem cells which are able to differentiate into cardiomyocytes, and ii) a hydrogel comprising silylated biomolecule, for use for treating heart failure, in particular heart failure following myocardial infarction.

Silylated biomolecule-based hydrogel for culturing cardiomyocytes and stem cells, and use of the hydrogel thereof for treating heart failure

The present invention is directed to a novel cement powder comprising an organic component consisting of one or more biocompatible and bioresorbable polymers and an inorganic component consisting of one or more calcium phosphate compounds. The invention also relates to the apatitic CPC resulting from the mixing of said cement powder with a liquid phase and setting.

Macroporous and highly resorbable apatitic calcium-phosphate cement

The invention concerns: &#x2014;a silylated biomolecule having the following formula (I): &#x2014;the process for the preparation of a silylated biomolecule of formula (I), &#x2014;the use of a silylated biomolecule of formula (I) to functionalize the surface of a support, &#x2014;a process for the preparation of a hydrogel by use of a silylated biomolecule of formula (I), the hydrogel obtainable by said process, &#x2014;said hydrogel as a biological tissue substitute, &#x2014;a composition comprising said hydrogel in a pharmaceutically acceptable vehicle, &#x2014;said composition for the release of active principle. 

Silylated biomolecules

The invention relates to the use of a silanised hydroxypropylmethylcellulose (HPMC) or silanised hydroxyethylcellulose (HEC) hydrogel, self-crosslinking as a function of pH, for the three-dimensional ex vivo culture of chondrocytes.

Use of a hydrogel for the culture of chondrocytes

Biomaterial composition and method for preparing same

Composition for biomaterial; preparation process

Growing community of inventors

Nantes, France

Pierre Weiss