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Roussel Uclaf

The Boots Company Plc

Pierre Smets

Rene Zalisz

Armelle Bonfils

Abdel Karim Braham

A method for facilitating the healing of skin comprising applying topically to skin a composition containing an amount of a lipopolysaccharide extracted from gram negative bacteria effective to facilitate skin healing.

Skin healing method

A sequence of anti-direction, anti-messenger RNA oligonucleotides of .alpha.-TNF characterized in that it possesses the structure of the formula ##STR1## wherein X is hydrogen, or a sequence of 1 to 17 oligonucleotides in free form, in alkylated form, in sulfurated form or in the form of a poly L-lysine derivative useful for stopping the production of .alpha.-TNF.

Oligonucleotides that inhibit production of .alpha.-tumor necrosis factor

A sulfate derivative of galactan extracted from Klebsiella mainly comprised of sulfate neutral oses in a proportion of 20 to 90% of hydroxyls and their preparation and method of use.

Sulfate derivatives of galactan extracted from Klebsiella

A dermatological hair growth stimulating composition containing an effective amount of a glycoprotein extract of gram negative bacteria as the growth stimulant and a method of stimulating hair growth.

Novel dermatological composition and method

An acylglycan extract of Klebsiella consisting essentially of about 80% of neutral oses, about 20% of lipids and less than 2% of proteins and having a molecular weight of approximately 12,500 and a process for obtining them which have antiallergic and immunomodulating properties.

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Villennes sur Seine, France

Pierre Smets