Science Union Et Cie

Science Union Et Cie, Societe Francaise De Recherche Medicale

Science Union Et Cie, Societe Francaise De Recherche Medical

Science Union Et Cie, Societe Francaise De Recherche Med.

Pierre Roger

Charles E Malen

Michel Laubie

Xavier B Pascaud

Jean-Claude Poignant

This invention relates to trifluorethylamines and to a process for producing the same. These trifluorethylamines are substituted on the nitrogen atom with a lower alkyl or a cyclo lower alkyl radical. They are endowed with interesting pharmacological properties.

2-[Trifluoroethylamine]oxazolines

This invention relates to novel substituted aryl lower alkamine and more precisely to arylmethylamine, the methyl group of which is substituted with one more polyfluoromethyl radicals. This invention also relates to the process for producing said compounds. The resulting compounds have pharmacological utility and may be used as a drug in human and veterinary medicine.

Novel aryltrifluoroethylamines and processes for producing the same

Certain phenyl amines have been prepared wherein the 'methyl' carbon is substituted with a polyfluoroalkyl radical. The compounds form acid addition salts, exist in resolvable stereoisomeric forms, and are useful for treating hypertension. Formulations for human and veterinary medicine are described, as well as methods of use.

Oxazoline (trifluoroethyl) amine

This invention relates to omega-mercaptopropionylamides, the nitrogen atom of which is included as a ring atom of a cyclic amino acid. The application also discloses a process for producing said compounds which comprises reacting an omega-mercaptopropionic acid, or a functional derivative thereof, with a cyclic amino acid. This invention further relates to pharmaceutical compositions incorporating such an omega-mercaptopropionylamide as active ingredient together with a pharmaceutically-acceptable carrier or vehicle, and a method of employing said compounds. They find a use in human therapy, namely, as antihypertensive agents.

Thiopropionamides, and the pharmaceutical compositions

Certain arylmethyl amines have been prepared wherein the 'methyl' carbon is substituted with a polyfluoroalkyl radical. The compounds form acid addition salts, exist in resolvable stereoisomeric forms, and are useful for treating hypertension. Formulations for human and veterinary medicine are described, as well as methods of use.

Aryltrifluoroethylamines

This invention relates to novel N-acyl anilines, to a process for their preparation and to pharmaceutical compositions containing them. The N-acyl anilines are obtained by condensing a substituted aniline with an aminolower alkyl carboxylic acid or a functional derivative thereof. The compounds of the invention have therapeutic utility namely in the gastro-enterologic field.

N-Acyl anilines used to inhibit gastric hypersecretion

This invention relates to novel .omega.-benzylamino alkanoic acids, to their salts with an organic or mineral base or with an organic or mineral acid. These alkanoic acids may be in a racemic form or resolved into their optically-active enantiomers. They are produced by condensing an oxoalkanoic acid with a benzylamine under reducing conditions. This invention also relates to .omega.-benzylamino alkanoic amides and to .omega.-benzylamino alkanoic acid esters. They have therapeutical use, namely in the psychotherapeutical field. They are utilized in the form of pharmaceutical compositions.

Benzylamino alkanoic acid derivatives, using compositions containing the

This invention relates to ortho-alkoxy anilines having the amino group substituted with an amino lower alkyl carboxylic residue, as well as their physiologically-compatible acid-addition salts and their optically-active isomers. This invention also relates to processes for making the same in which an ortho-alkoxy aniline is reacted with a lower alkanoic acid or a functional derivative thereof. The compounds of the invention have therapeutical utility namely for the prevention or treatment of digestive disorders and gastric ulcers.

Alkoxy anilides and pharmaceutical compositions

N-acyl anilines, useful for gastro-enterological disorders

Alkoxy anilides process for preparing the same and pharmaceutical

This invention relates to ortho-alkoxy anilines having the amino group substituted with an amino lower alkyl carboxylic residue, as well as their physiologically-compatible acid-addition salts and their optically-active isomers.

Growing community of inventors

St-Cloud, France

Pierre Roger