Syngenta Crop Protection, Inc.

Merial Limited

Syngenta Participations Ag

Syngenta Corp Protection LLC

Pierre Marcel Jung

Thomas Pitterna

Peter Maienfisch

Laura Quaranta

Fiona Murphy Kessabi

Ottmar Franz Hueter

Jerome Yves Cassayre

Werner Zambach

William Lutz

Peter Renold

Jérôme Yves Cassayre

Andrew Edmunds

Michel Muehlebach

Andre Jeanguenat

Patricia Durieux

Christopher Richard Syles Godfrey

Polycyclic derivatives of formula I wherein the substituents are as defined in claim, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.

Pesticidally active polycyclic derivatives with sulfur containing substituents

A compound of formula (I), wherein A, A, A, A, R, R, G, G, Qand Qare as defined in claim; or salts or N-oxides thereof. Furthermore, the present invention relates to processes and intermediates for preparing compounds of formula (I), to insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and to methods of using them to combat and control insect, acarine, mollusc and nematode pests. 

Insecticidal compounds

A compound of formula (I): wherein A, A, A, A, R, R, G, G, Qand Qare as defined in claim; or a salt or N-oxide thereof. Furthermore, the present invention relates to processes and intermediates for preparing compounds of formula (I), to insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and to methods of using them to combat and control insect, acarine, mollusc and nematode pests. 

What is described are a compound of the formula wherein

Avermectin B1 and avermectin B1 monosaccharide derivatives having an alkoxymethyl substituent in the 4&#x2033;-or 4'-position

Novel heteroaromatic compounds of formula (I): wherein A, A, A, R, R, G, G, Qand Qare as defined in claim; or salts or N-oxides thereof. Furthermore, the present invention relates to processes for preparing compounds of formula (I), to insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and to methods of using them to combat and control insect, acarine, mollusc and nematode pests. 

Certain derivatives of avermectin, avermectin monosaccharide and avermectin aglycone, having on the 4&#x2033;, 4' or 13 position, respectively, a 6-membered cyclic acetal with a substituent on position 2, that are useful in controlling pests, in particular pests that are harmful to crop plants and to its propagation material, such as representatives of the class insecta, the order acarina and the class nematode, are provided. 

Derivatives of avermectin, avermectin monosaccharide and avermectin aglycone

Avermectin B1 and avermectin B1 monosaccharide derivative compounds having an alkoxymethyl substituent in the 4&#x2033;- or 4'-position; a process for preparing and using these compounds and their tautomers; pesticides whose active compound is selected from these compounds and their tautomers; and a process for preparing these compounds and compositions are provided.

Avermectin B1 and avermectin B1 monosaccharide derivatives having an alkoxymethyl substituent in the 4&#x2033; -or 4'-position

Described is a compound of the formula (I) wherein the bond between carbon atoms 22 and 23 is a single or double bond; m is 0 or 1; R, is C-Calkyl, C-Ccycloalkyl or C-Calkenyl; and either (A) Ris &#x2014;N(R)R, and (1) X is 0, wherein Ris, for instance, hydrogen, unsubstituted or mono- to pentasubstituted C-Calkyl, and Ris, for instance, mono- to pentasubstituted C-Calkyl, unsubstituted or mono- to pentasubstituted C-Ccycloalkyl; or (2) X is S, wherein Ris, for instance, hydrogen, unsubstituted or mono- to pentasubstituted C-Calkyl, and Ris, for instance, hydrogen, unsubstituted or mono- to pentasubstituted C-Calkyl; or (3) X is 0 or S, wherein Rand Rtogether are, for instance, a three- to seven membered alkylene or a four- to seven-membered alkenylene bridge; or (B) Ris OR, X is 0 or S, wherein Ris, for instance, C-Calkyl, mono- to pentasubstituted C-Calkyl; or, if appropriate, an E/Z isomer, E/Z isomer mixture and/or tautomer thereof, in each case in free form or in salt form; such a compound demonstrates pesticidal activity. 

Avermectins and avermectin monosacharides substituted in the 4'-and 4&#x2033; position having pesticidal properties

Avermectin and avermectin monosaccharaide compounds, derivatives, and compositions thereof are provided as well as processes for preparing such compounds, derivatives, and compositions. Intermediates in the preparation of avermectin and avermectin monosaccharaide derivatives and methods of controlling pests are also provided. The avermectin and avermectin monosaccharaide derivatives are demonstrated as useful in controlling pests, in particular pests that are harmful to crop plants and to its propagation materials, such as representatives of the class insecta, the order Acarina and the class nematede.

Avermectin and avermectin monosaccharide substituted in the 4&#x2033;- and 4&#x2033; position respectively

What is described are a compound of the formula (I) Wherein U is &#x2014;N(R)ORor &#x2014;N(O)&#x2550;C(R)R); n is 0 or 1; X&#x2014;Y is &#x2014;CH&#x2550;CH&#x2014; or &#x2014;CH&#x2014;CH&#x2014;; Ris C-Calkyl, C-Ccycloalkyl or C-Calkenyl; Rand Rare, for example; independently from each other, &#x2014;Q, &#x2014;C(&#x2550;O)&#x2014;Z&#x2014;Q or &#x2014;CN; Rand Rare, independently from each other, &#x2014;Q, &#x2014;C(&#x2550;O)&#x2014;Z&#x2014;Q or &#x2014;CN; or Rand Rtogether are a three- to seven membered alkylene or alkenylene bridge, which is unsubstituted or mono- to tri-substituted; Z is a bond, O or &#x2014;NR&#x2014;; Q is H, C-Calkyl, C-Calkenyl, C-Calkynyl, C-C-Cycloalkyl, C-C-cycloalkenyl, aryl, or heterocyclyl, which are unsubstituted or mono- to pentasubstituted; Ris for example H, C-Calkyl, hydroxy-C-Calkyl, C-Ccycloalkyl or C-Calkenyl; or, if appropriate, an E/Z isomer, E/Z isomer mixture and/or tautomer thereof; a process for preparing these compounds, their isomers and tautomers and the use of these compounds, their isomers and tautomers; pesticidal compositions whose active compound is selected from these compounds and their tautomers; intermediates for the preparation of the said compounds of the formula (I), methods for the preparation of the compounds of the formula (I), and a method for controlling pests using these compositions. 

Avermectin and avermectin monosaccharide derivatives substituted in the 4&#x2033;-or 4'-position having pesticidal properties

Disclosed are compounds of the formulain which n is 0 or 1; X&#x2014;Y is &#x2014;CH&#x2550;CH&#x2014; or &#x2014;CH&#x2014;CH&#x2014;; Z is &#x2014;C(&#x2550;O)&#x2014;, &#x2014;C(&#x2550;S)&#x2014; or &#x2014;SO&#x2014;; Ris C-Calkyl, C-Ccycloalkyl or C-Calkenyl; and Ris R-Z-, R&#x2014;O-Z-, Ror -Z-N(R)(R); Q is O or &#x2014;N&#x2014;R; Rand Rare for example H, CCalkyl, C-Calkenyl, C-Calkynyl, C-Czcycloalkyl, C-Ccycloalkenyl, aryl or heterocyclyl; Ris for example H, C-Calkyl, hydroxy-C-Calkyl, C-Ccycloalkyl, C-Calkenyl, C-Calkynyl, phenyl or benzyl; Rand Rare for example, H, unsubstituted or mono- to pentasubstituted C-Calkyl, unsubstituted or mono- to pentasubstituted C-Calkenyl or, if appropriate, an E/Z isomer, E/Z isomer mixture and/or tautomer thereof, in each case in free form or in salt form, are useful as pesticides. 

Avermectin and avemectin monosaccharide derivatives substituted in the 4&#x2033;-  or 4'-position having pesticidal properties

A compound of formula (I) wherein the bond between carbon atoms 22 and 23 may be a single or a double bond; Ris C-Calkyl, C-Ccycloalkyl, or C-Calkenyl; Rand Rare, for example, independently of each other hydrogen, C-Calkyl, C-Ccycloalkyl, C-Calkenyl, C-Calkynyl, aryl or heteroaryl; and, where applicable, to E/Z isomers, mixtures of E/Z isomers, diastereomers and/or tautomers, in each case in free form or in salt form; pesticidal compositions in which the active ingredient has been selected from those compounds and their tautomers; and a method of controlling pests using those compositions are described. 

Growing community of inventors

Stein, Switzerland

Pierre Marcel Jung