Oread Laboratories, Inc.

Pierre M De Montigny

Arnold J Repta

Takeru Higuchi, Deceased

Larry A Sternson

John F Stobaugh

By Kenji Higuchi, Co-executor

John F Stabaugh

Kenji W Higuchi, Co-executor

By Martin Dickinson, Jr, Co-executor

There is provided a fluorescent adduct which is amenable to detection by fluorometric and electrochemical techniques. The adduct is of the formula: ##STR1## wherein X is a radical derived from a primary amine of the formula X--NH.sub.2 and where R.sub.1 --R.sub.6 are selected from various organic or inorganic substituents.

Polycyclic nitriles

A method of assaying primary amines or cyanide is disclosed. The process is carried out by reacting a substituted or unsubstituted naphthalene-2,3-dicarboxaldehyde or o-phthalaldehyde, reactive with primary amines and cyanide, with cyanide ions and at least one primary amine to form an adduct amenable to fluorometric or electrochemical assaying techniques. The adduct is then fluorometrically or electrochemically assayed. Also disclosed are 1-cyano-benz[f]isoindole adducts.

Assaying method for primary amines using aromatic dialdehydes

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Fords, NJ, United States of America

Pierre M De Montigny