Philip Morris Products S.a.

Pierre Herve

Sandro Steiner

Shoaib Majeed

Ricardo Cali

Antonin Sandoz

Jan Verbeeck

Joern Patscher

Johan Valette

Danny Hirdes

Andreas Loeb

Fabrice Teseo

There is described herein a perforated structure for use in a simulated respiratory tract, the structure comprising a perforated envelope housing one or more branched channels, wherein each perforation is an open terminal of a branch. Also described is a pump for displacing a volume of gas that includes one or more branched channels, such as the perforated structure described herein. Use of the pump in a system for determining the interaction between a test atmosphere and a simulated respiratory tract is also described, together with methods and uses of such a system.

Perforated structure

There is described herein a system for determining the interaction between a test atmosphere and a simulated respiratory tract, said system comprising: (a) a first pump comprising: (i) a chamber configured for containing a first volume of gas comprising a test atmosphere; (ii) a first port adapted for receiving and outputting gas and comprising a valve for regulating the flow of gas through the first port, said valve being moveable between open and closed positions, wherein in the open position said valve is openable towards a test atmosphere or surrounding air; (iii) a second port adapted for outputting and receiving gas and comprising a valve for regulating the flow of gas through the second port, said valve being moveable between open and closed positions; (iv) a piston plate in the chamber, said piston plate comprising one or more apertures for the uptake or inflow of gas into the chamber wherein one or more, or each, of the apertures include a valve that is movable between open and closed positions and is capable of regulating the uptake or inflow of gas; (b) a second pump comprising: (i) a chamber configured for containing a second volume of gas, wherein the first and second volumes of gas are different; (ii) a port adapted for receiving and outputting gas; and (iii) a motor for controlling the operation of the second pump; (c) a connecting structure operable to transmit the gas from the first pump into the second pump; and (d) one or more openings in the first pump or the second pump or the walls of the connecting structure or a combination of two or more thereof, said openings being capable of receiving a module for containing a cell culture medium or for monitoring conditions in the chamber or for gas sampling or for gas characterisation.

Simulated respiratory tract

An apparatus is provided, including: a housing; a first assessment section defining a first airflow pathway and including a first conduit including inlet and outlet ends, the inlet end to receive a mouth end of an aerosol-generating system or a smoking article, a first pump in fluid communication with the first conduit outlet end and to draw fluid through the first conduit from the inlet end to the outlet end, and a first cover arranged on the housing; and a second assessment section defining a second airflow pathway and including a second conduit including inlet and outlet ends, the inlet end to receive a mouth end of an aerosol-generating device or a smoking article, a second pump in fluid communication with the second conduit outlet end and to draw fluid through the second conduit from the inlet end to the outlet end, and a second cover arranged on the housing.

Aerosol-generating device comparator

Growing community of inventors

Daillens, Switzerland

Pierre Herve