Sanofi-Aventis

Pierre Fraisse

Pierre Casellas

Samir Jegham

Daniel Floutard

Bernard Labeeuw

Pierre Carayon

Stephane Hourcade

The disclosure relates to 2-carbamide-4-phenylthiazole derivatives having the following general formula (I): wherein R, R, R, Y and p are as defined in the disclosure. The disclosure also relates to pharmaceutical compositions containing a compound of formula (I), to processes for preparing the compounds of formula (I), and to methods of using the compounds of formula (I).

2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof

The invention relates to 2-acylamino-4-phenylthiazole derivatives of general formula (I): pharmaceutically acceptable acid-addition salts thereof, hydrates or solvates of such derivatives or such pharmaceutically acceptable acid addition salts, intermediates thereto, processes for the preparation thereof, and therapeutic application thereof.

2-acylamino-4-phenylthiazole derivatives, preparation thereof and therapeutic application thereof

The disclosure concerns 2-carbamide-4-phenylthiazole derivatives of general formula (I). The disclosure also concerns pharmaceutical compositions containing a compound of general formula (I) and to processes for preparing and methods of using compounds of general formula (I). 

2-Carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof

The disclosure relates to 2-amido-4-phenylthiazole derivatives of general formula (I) below: in which R, R, R, Y, m, n, and p are as defined in the disclosure; as well as to their isomers, salts and solvates, to the pharmaceutical compositions containing them and to the therapeutic use thereof.

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Juvignac, France

Pierre Fraisse