Rhone-poulenc Sante

Rhone-poulenc Nutrition Animale

Pierre Ardaillon

Christian Prud'Homme

Paul Bourrain

Pierre Autant

Andre Cartillier

Christine Franzoni

A process for coating at least one medicinal and/or foodstuff active principle useful for ruminants. At least one monomer is polymerized in an oil-in-water emulsion in the presence of a surfactant to synthesize a pH-sensitive-polymer composition, the composition being obtained in an oil-in-water emulsion. Without isolation of the pH-sensitive polymer, the oil-in-water emulsion is used to coat the active principle, preferably methionine or lysine or a derivative thereof. The pH-sensitive polymer is not dissolved in an organic solvent(s) in either the polymerization or coating steps. The pH-sensitive polymer is stable at pH 6 but at pH 2, the coated active principle is released.

Process for coating active principles using a pH-sensitive polymer

A new method of coating an active principle which comprises the step of coating an active principle with an aqueous emulsion or dispersion containing one or more pH-sensitive polymers.

Method for coating active principles with a pH-sensitive polymer

Enzymatically degradable compositions for the coating of feed additives intended for ruminants, including zein, at least one hydrophobic substance, optionally at least one non-water-soluble polymer and at least one inorganic filler. The compositions are used to coat feed additives such as medicinal products, vitamins and amino acids.

Enzymatically degradable coating compositions for feed additives

Granules containing feed additives for ruminants are coated with an enzymatically degradable composition, consisting of: zein in combination with a non-water-soluble polymer and optionally a plasticizing agent, or zein in combination with a hydrophobic substance and optionally a non-water-soluble polymer.

Granules for feeding ruminants with an enzymatically degradable coating

A composition for coating a biologically active substance, which is stable in a medium with a pH greater than or equal to 5 and which enables the active substance to be released in a medium with a pH less than or equal to 3.5, consisting of a basic amino copolymer (preferably vinyl-pyridine/styrene copolymer) and a hydrophobic substance with a melting point greater than 60.degree. C. (preferably stearic acid), the hydrophobic substance content being between 50 and 90% of the total mass of the coating, and granules comprising a nucleous containing the biologically active substance, coated with this composition.

Growing community of inventors

Saint-Priest, France

Pierre Ardaillon