Afx Inc.

Maquet Cardiovascular LLC

Pierre-Antoine Chapelon

Dany Berube

Hiep Nguyen

Faouzi Kallel

An instrument assesses the transmurality of an ablation lesion from a first surface of a targeted biological tissue to an opposed second surface thereof. The instrument includes at least a first electrode operably attached to an ablation instrument adapted to engage a tissue first surface, and at least a second electrode adapted to engage a tissue second surface, the at least second electrode positioned generally opposed to the at least first electrode. Alternatively, the at least second electrode may be adapted to be placed within a chamber of an organ. These electrodes facilitate measuring at least one of conduction time, conduction velocity, phase angle, and impedance through at least a portion of the targeted tissue to determine the transmurality of the ablation lesion.

Apparatus and method for assessing transmurality of a tissue ablation

An instrument is provided to assess the transmurality of an ablation lesion from a first surface of a targeted biological tissue to an opposed second surface thereof. The instrument includes at least a first electrode operably attached to an ablation instrument adapted to engage a tissue first surface, and at least a second electrode adapted to engage a tissue second surface, the at least second electrode positioned generally opposed to the at least first electrode. Alternatively, the at least second electrode may be adapted to be placed within a chamber of an organ. These electrodes each measure at least one of conduction time, conduction velocity, phase angle, and impedance through at least a portion of the targeted tissue to determine the transmurality of the ablation lesion.

An ablation system incorporating an enhanced deflectable distal portion, is provided. The system includes an elongated tubular member having a deflectable distal portion adapted to assume a specific predetermined or predefined shape when deployed. The predetermined shape allows for the creation of a desired uniform energy emission pattern with respect to a target tissue, such that energy may be directed toward the target tissue independent of an approach orientation of the ablation system. The energy pattern results in the creation of a desired tissue ablation. The ablation system may further comprise a steering system which aides in directing the distal portion toward a target tissue site. The steering system may alternatively be incorporated into a separate guiding catheter as part of the ablation system.

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Carrieres sur Seine, France

Pierre-Antoine Chapelon