Indena S.p.a.

Other

Inverni Della Beefa S.p.a.

Piero Valenti

Ezio Bombardelli

Giorgio Pifferi

Salvatore Malandrino

Paolo Da Re

Chalcone coumarins

Chalcones

Derivatives of flavones, xanthones and coumarins

The invention relates to a novel class of compounds that have structures related to certain naturally occurring or synthetic chalcones. The invention also relates to pharmaceutical compositions comprising the compounds and methods for treating certain disorders using the pharmaceutical compositions. The invention further relates to a process for synthesizing the novel class of compounds.

Chalcones having antiproliferative activity

The novel compounds 3,6-Disubstituted xanthen-9-one of formula I ##STR1## in which R is a C.sub.3 -C.sub.8 linear, branched or cyclic alkyl and R.sub.1 is linear, branched C.sub.1 -C.sub.8 alkyl or cyclic C.sub.3 -C.sub.8 alkyl or --OR in which R is as defined hereinabove, exhibit bone resorption inhibiting activity. Pharmaceutical compositions are described.

Xanthone derivatives, their preparation and use

Growing community of inventors

Bologna, Italy

Piero Valenti