Carlo Erba S.p.a.

Farmitalia Carlo Erba S.p.a.

Other

PierNicola Giraldi

Gianfederico Doria

Maria L Corno

Francesco Lauria

Marcello Tibolla

Ciriaco Romeo

Piero Sberze

Ada Buttinoni

Raffaele Tommasini

Willy Logemann

Giovanni Biasoli

Giuliano Nannini

Giriaco Romeo

3,4-Dihydro-quinazoline derivatives, such as 6-carboxy-2-(2'-ethoxy-phenyl)-3,4-dihydro-4-oxo-quinazoline, are disclosed. The compounds possess anti-allergy properties and can be used for the treatment of allergic conditions.

3,4-Dihydro-quinazoline derivatives

Substituted 2-vinyl-chromones are disclosed, wherein the chromone ring has an alkyl or alkenyl substituent at the 3-position, and a styryl substituent at the 2-position. The compounds exhibit anti-allergy activity and can be used to treat allergic conditions.

Substituted 2-vinyl-chromones and process for their preparation

Substituted 2-vinyl chromones are disclosed, wherein the chromone ring has an alkyl or alkenyl substituent at the 3-position, and a styryl substituent at the 2-position. The compounds exhibit anti-allergy activity and can be used to treat allergic conditions.

Substituted 2-vinyl chromones are disclosed, wherein the chromone ring has an alkyl or alkenyl substituent at the 3-position, and a pyridyl-vinyl substituent at the 2-position. The compounds exhibit anti-allergy activity and can be used to treat allergic conditions.

Substituted 2-vinyl chromones are disclosed, wherein the chromone ring has an alkyl or alkenyl substituent at the 3-position, and an unsubstituted furyl substituent at the 2-position. The compounds exhibit anti-allergy activity and can be used to treat allergic conditions.

3,4-Dihydro-4-oxo-quinazoline derivatives substituted in the 2-position by a substituted phenyl group are disclosed. The derivatives possess anti-allergy properties and can be used for the treatment of allergic conditions.

2-Disubstituted phenyl-3,4-dihydro-4-oxo-quinazoline derivatives and

6-CARBOXY-FLAVONE DERIVATIVES ARE DISCLOSED, WHEREIN THE FLAVONE DERIVATIVE IS SUBSTITUTED AT THE 2'-POSITION WITH AN ALKOXY GROUP, WHICH MAY BE SUBSTITUTED, AND WHEREIN THE PHENYL RING ALSO CARRIES AN ALKYL SUBSTITUENT. The flavone derivatives exhibit anti-allergic activity and spasmolytic activity.

6-Carboxy-flavone derivatives and process for their preparation

Substituted 2-vinyl-chromones are disclosed wherein the chromone ring has an alkyl or alkenyl substituent at the 3-position. The compounds exhibit anti-allergy activity and can be used to treat allergic conditions.

2-Vinyl-chromones and pharmaceuticals therewith

Chromone compounds carrying a pyridyl substituent at the 2-position are disclosed, such as, for instance, 6-carboxy-2-(2'-pyridyl)-chromone. The disclosed compounds are useful in the treatment of allergies.

5:6-Benzo-.gamma.-pyrone derivatives and process for their preparation

Isoindoline derivatives are disclosed, as for instance of the formula: ##STR1## and methods of preparation of these compounds, such as the reaction of o-cyano-benzylbromide with a compound of formula ##STR2## and subsequent saponification. The compounds possess analgesic and anti-inflammatory activity.

Isoindoline derivatives for treating pain

Chromone compounds carrying a pyrazinyl substituent at the 2-position are disclosed, such as, for instance, 6-carboxy-2-(2'-pyrazinyl)-chromone. The disclosed compounds are useful in the treatment of allergies.

6-Carboxy-2-(2'-pyrazinyl)-chromones and esters thereof

Substituted 6-carboxy flavones are disclosed, such as, for instance, 6-carboxy-2'-isopropoxy-flavone. Such flavone derivatives possess anti-allergic activity, decrease airway resistance and increase pulmonary compliance. In addition, the compounds possess anti-ulcer activity.

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Milan, Italy

PierNicola Giraldi