Ares Trading S.a.

Eurand International S.p.a.

Vectorpharma International Corporation

Merck Serono S. a.

Messer Italia S.p.a.

Pierandrea Esposito

Maria Dorly Del Curto

Fabio Carli

Daniela Chicco

Jean-Pierre Gotteland

Pascale Gaillard

Luca Dobetti

Isabelle Jeanclaude-Etter

Mario Maio

Luca Donati

Daniela Lombardi

Luigi Boltri

Ilaria Zambaldi

Silvia Pompili

Andrea Leonardi

Stefania Bertero

Simone Grandolini

Nicoletta Coceani

Mauro Menegoli

Leonardo Galli

The present invention is related to pharmaceutical Poloxamer hydrogel formulations containing an interferon. In particular, the invention relates to sustained release hydrogel formulations of interferon-beta, method of preparation and use thereof.

Hydrogel interferon formulations

The present invention is related to macrogol glyceride pharmaceutical formulations containing benzothiazole derivatives. In particular, the invention is related to benzothiazole stearoyl macrogol pharmaceutical formulations, method of preparation and use thereof.

Benzothiazole formulations and use thereof

This invention relates to Lipid Microparticles consisting of lipids enriched in amphiphilic components, which promote the incorporation of peptides and/or protein, process for obtaining them as well as use thereof. A cryogenic micronization manufacturing process for their preparation is also disclosed.

Lipid microparticles by cryogenic micronization

The invention provides a biphasic multicomponent pharmaceutical composition consisting of an oil phase and a water phase, comprising one or more lipophilic or oil carrier, one or more hydrophilic or aqueous carrier, one or more ionic or nonionic type surfactant, one or more cosurfactant, one or more active principle for pharmaceutical use, and a compound able to modify the partition of the active principle between said phases selected from the group consisting of N- methyl pyrrolidone (NMP), isopropyl alcohol, propylene glycol, ethoxy-di-glycol, &bgr;-cyclodextrin, hydroxypropyl &bgr;-cyclodextrin and dimethyl &bgr;-cyclodextrin. The invention also provides a method for making the composition.

Biphasic multicomponent pharmaceutical dosage forms containing substances able to modify the partitioning of drugs

The pharmaceutical compositions including a slightly soluble drug incorporated in a water-swellable, but water-insoluble cross-linked polymer, a surface active agent, and an oil show much improved dissolution and, consequently, bioavailability in respect of the drug as is or used with a polymeric carrier of said type.

Pharmaceutical compositions including a drug, a cross-linked polymeric

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Ivrea, Italy

Pierandrea Esposito